Suchergebnisse - "Leow, Jacqueline Wen Hui"

PubPharm (13)

1

CYP2J2-mediated metabolism of arachidonic acid in heart : A review of its kinetics, inhibition and role in heart rhythm control

enthalten in: Pharmacology & therapeutics | 2024

von Leow, J. | Chan, E.

2

Investigating the relevance of CYP2J2 inhibition for drugs known to cause intermediate to high risk torsades de pointes

enthalten in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences | 2023

von Leow, J. | Gu, Y. | Chan, E.

3

Development and verification of a physiologically based pharmacokinetic model of dronedarone and its active metabolite N-desbutyldronedarone : Application to prospective simulation of complex drug-drug interaction with rivaroxaban

enthalten in: British journal of clinical pharmacology | 2023

von Leow, J. | Ang, X. | Chan, E.

4

Development and verification of a physiologically based pharmacokinetic model of dronedarone and its active metabolite N‐desbutyldronedarone : Application to prospective simulation of complex drug–drug interaction with rivaroxaban

enthalten in: British Journal of Clinical Pharmacology | 2023

von Leow, J. | Ang, X. | Chan, E.

5

Site-directed deuteration of dronedarone preserves cytochrome P4502J2 activity and mitigates its cardiac adverse effects in canine arrhythmic hearts

enthalten in: Acta pharmaceutica Sinica. B | 2022

von Karkhanis, A. | Venkatesan, G. | Kambayashi, R. | +9

6

Atypical kinetics of cytochrome P450 enzymes in pharmacology and toxicology

enthalten in: Advances in pharmacology (San Diego, Calif.) | 2022

von Leow, J. | Tang, L. | Chan, E.

7

Atypical kinetics of cytochrome P450 2J2 : Epoxidation of arachidonic acid and reversible inhibition by xenobiotic inhibitors

enthalten in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences | 2021

von Leow, J. | Verma, R. | Lim, A. | +2

8

How the Deuteration of Dronedarone Can Modify Its Cardiovascular Profile : In Vivo Characterization of Electropharmacological Effects of Poyendarone, a Deuterated Analogue of Dronedarone

enthalten in: Cardiovascular toxicology | 2020

von Kambayashi, R. | Hagiwara-Nagasawa, M. | Kondo, Y. | +10

9

How the Deuteration of Dronedarone Can Modify Its Cardiovascular Profile: In Vivo Characterization of Electropharmacological Effects of Poyendarone, a Deuterated Analogue of Dronedarone

enthalten in: Cardiovascular toxicology | 2020

von Kambayashi, R. | Hagiwara-Nagasawa, M. | Kondo, Y. | +10

10

How the Deuteration of Dronedarone Can Modify Its Cardiovascular Profile: In Vivo Characterization of Electropharmacological Effects of Poyendarone, a Deuterated Analogue of Dronedarone

enthalten in: Cardiovascular toxicology | 2020

von Kambayashi, R. | Hagiwara-Nagasawa, M. | Kondo, Y. | +10