Suchergebnisse - "Lavecchia, Antonio"

PubPharm (25)

1

A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition

enthalten in: Journal of medicinal chemistry | 2023

von Laghezza, A. | Cerchia, C. | Genovese, M. | +15

2

A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity

enthalten in: European journal of medicinal chemistry | 2022

von Sblano, S. | Cerchia, C. | Laghezza, A. | +11

3

Thiazolidinedione "Magic Bullets" Simultaneously Targeting PPARγ and HDACs : Design, Synthesis, and Investigations of their In Vitro and In Vivo Antitumor Effects

enthalten in: Journal of medicinal chemistry | 2021

von Tilekar, K. | Hess, J. | Upadhyay, N. | +8

4

Chiral phenoxyacetic acid analogues inhibit colon cancer cell proliferation acting as PPARγ partial agonists

enthalten in: Scientific reports | 2019

von Sabatino, L. | Ziccardi, P. | Cerchia, C. | +6

5

Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation

enthalten in: Journal of medicinal chemistry | 2018

von Laghezza, A. | Piemontese, L. | Cerchia, C. | +9

6

Selective PPARγ modulators for Type 2 diabetes treatment : how far have we come and what does the future hold?

enthalten in: Future medicinal chemistry | 2018

von Lavecchia, A. | Cerchia, C.

7

Novel Benzylidene Thiazolidinedione Derivatives as Partial PPARγ Agonists and their Antidiabetic Effects on Type 2 Diabetes

enthalten in: Scientific reports | 2017

von Yasmin, S. | Capone, F. | Laghezza, A. | +10

8

New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity

enthalten in: European journal of medicinal chemistry | 2017

von Piemontese, L. | Cerchia, C. | Laghezza, A. | +11

9

A compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative ability

enthalten in: Scientific reports | 2017

von Vasaturo, M. | Fiengo, L. | De Tommasi, N. | +9

10

Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode

enthalten in: Scientific reports | 2016

von Capelli, D. | Cerchia, C. | Montanari, R. | +6