Suchergebnisse - "Lavecchia, Antonio"

PubPharm (17)

1

Discovery of a Novel Inhibitor of Human Purine Nucleoside Phosphorylase by a Simple Hydrophilic Interaction Liquid Chromatography Enzymatic Assay

enthalten in: ChemMedChem | 2021

von Rabuffetti, M. | Rinaldi, F. | Lo Bianco, A. | +7

2

A Series of Ferulic Acid Amides Reveals Unexpected Peroxiredoxin 1 Inhibitory Activity with in vivo Antidiabetic and Hypolipidemic Effects

enthalten in: ChemMedChem | 2021

von Yasmin, S. | Cerchia, C. | Badavath, V. | +13

3

Inhibition mechanism of naphthylphenylamine derivatives acting on the CDC25B dual phosphatase and analysis of the molecular processes involved in the high cytotoxicity exerted by one selected derivative in melanoma cells

enthalten in: Journal of enzyme inhibition and medicinal chemistry | 2020

von Aliotta, F. | Nasso, R. | Rullo, R. | +8

4

Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors : Design, Synthesis, Inhibition Mechanism, and in Vitro Efficacy against Melanoma Cell Lines

enthalten in: Journal of medicinal chemistry | 2019

von Cerchia, C. | Nasso, R. | Mori, M. | +10

5

Recent advances in developing PCSK9 inhibitors for lipid-lowering therapy

enthalten in: Future medicinal chemistry | 2019

von Lavecchia, A. | Cerchia, C.

6

Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation

enthalten in: Journal of medicinal chemistry | 2018

von Laghezza, A. | Piemontese, L. | Cerchia, C. | +9

7

CDC25 Inhibition in Acute Myeloid Leukemia-A Study of Patient Heterogeneity and the Effects of Different Inhibitors

enthalten in: Molecules (Basel, Switzerland) | 2017

von Brenner, A. | Reikvam, H. | Rye, K. | +3

8

Ligand-based chemoinformatic discovery of a novel small molecule inhibitor targeting CDC25 dual specificity phosphatases and displaying in vitro efficacy against melanoma cells

enthalten in: Oncotarget | 2015

von Capasso, A. | Cerchia, C. | Di Giovanni, C. | +6

9

Therapeutic targeting the cell division cycle 25 (CDC25) phosphatases in human acute myeloid leukemia--the possibility to target several kinases through inhibition of the various CDC25 isoforms

enthalten in: Molecules (Basel, Switzerland) | 2014

von Brenner, A. | Reikvam, H. | Lavecchia, A. | +1

10

Discovery of new inhibitors of Cdc25B dual specificity phosphatases by structure-based virtual screening

enthalten in: Journal of medicinal chemistry | 2012

von Lavecchia, A. | Di Giovanni, C. | Pesapane, A. | +6