Suchergebnisse - "Kokot, Maja"

PubPharm (11)

1

Dynamic Profiling and Binding Affinity Prediction of NBTI Antibacterials against DNA Gyrase Enzyme by Multidimensional Machine Learning and Molecular Dynamics Simulations

enthalten in: ACS omega | 2024

von Kokot, M. | Minovski, N.

2

The overview of development of novel bacterial topoisomerase inhibitors effective against multidrug-resistant bacteria in an academic environment : From early hits to in vivo active antibacterials

enthalten in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences | 2024

von Zorman, M. | Hrast Rambaher, M. | Kokot, M. | +2

3

Exploring Alternative Pathways to Target Bacterial Type II Topoisomerases Using NBTI Antibacterials : Beyond Halogen-Bonding Interactions

enthalten in: Antibiotics (Basel, Switzerland) | 2023

von Kokot, M. | Novak, D. | Zdovc, I. | +3

4

Amide containing NBTI antibacterials with reduced hERG inhibition, retained antimicrobial activity against gram-positive bacteria and in vivo efficacy

enthalten in: European journal of medicinal chemistry | 2023

von Kokot, M. | Weiss, M. | Zdovc, I. | +5

5

Diminishing hERG inhibitory activity of aminopiperidine-naphthyridine linked NBTI antibacterials by structural and physicochemical optimizations

enthalten in: Bioorganic chemistry | 2022

von Kokot, M. | Weiss, M. | Zdovc, I. | +3

6

The Structural Features of Novel Bacterial Topoisomerase Inhibitors That Define Their Activity on Topoisomerase IV

enthalten in: Journal of medicinal chemistry | 2022

von Kokot, M. | Anderluh, M. | Hrast, M. | +1

7

Structurally Optimized Potent Dual-Targeting NBTI Antibacterials with an Enhanced Bifurcated Halogen-Bonding Propensity

enthalten in: ACS medicinal chemistry letters | 2021

von Kokot, M. | Weiss, M. | Zdovc, I. | +3

8

A Fine-Tuned Lipophilicity/Hydrophilicity Ratio Governs Antibacterial Potency and Selectivity of Bifurcated Halogen Bond-Forming NBTIs

enthalten in: Antibiotics (Basel, Switzerland) | 2021

von Kolarič, A. | Kokot, M. | Hrast, M. | +6

9

A Potent Mimetic of the Siglec-8 Ligand 6'-Sulfo-Sialyl Lewisx

enthalten in: ChemMedChem | 2020

von Kroezen, B. | Conti, G. | Girardi, B. | +9

10

A Potent Mimetic of the Siglec‐8 Ligand 6’‐Sulfo‐Sialyl Lewis x

enthalten in: ChemMedChem | 2020

von Kroezen, B. | Conti, G. | Girardi, B. | +9