Suchergebnisse - "Koh, Cho Yeow"

PubPharm (8)

1

5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors

enthalten in: ACS infectious diseases | 2016

von Zhang, Z. | Koh, C. | Ranade, R. | +11

2

A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens

enthalten in: Acta crystallographica. Section D, Biological crystallography | 2015

von Koh, C. | Siddaramaiah, L. | Ranade, R. | +8

3

Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening

enthalten in: Journal of biomolecular screening | 2015

von Pedró-Rosa, L. | Buckner, F. | Ranade, R. | +13

ErratumIn: J Biomol Screen. 2016 Jul;21(6):653. - PMID 27189835

4

Comparison of histidine recognition in human and trypanosomatid histidyl-tRNA synthetases

enthalten in: Biochimie | 2014

von Koh, C. | Wetzel, A. | de van der Schueren, W. | +1

5

Structures of Trypanosoma brucei methionyl-tRNA synthetase with urea-based inhibitors provide guidance for drug design against sleeping sickness

enthalten in: PLoS neglected tropical diseases | 2014

von Koh, C. | Kim, J. | Wetzel, A. | +10

6

Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design

enthalten in: Molecular and biochemical parasitology | 2013

von Koh, C. | Kim, J. | Napoli, A. | +5

7

Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection

enthalten in: Structure (London, England : 1993) | 2012

von Koh, C. | Kim, J. | Shibata, S. | +8

8

Urea-based inhibitors of Trypanosoma brucei methionyl-tRNA synthetase : selectivity and in vivo characterization

enthalten in: Journal of medicinal chemistry | 2012

von Shibata, S. | Gillespie, J. | Ranade, R. | +8

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