Suchergebnisse - "Koh, Cho Yeow"

PubPharm (6)

1

Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors

enthalten in: European journal of medicinal chemistry | 2016

von Huang, W. | Zhang, Z. | Barros-Álvarez, X. | +9

2

5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors

enthalten in: ACS infectious diseases | 2016

von Zhang, Z. | Koh, C. | Ranade, R. | +11

3

Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening

enthalten in: Journal of biomolecular screening | 2015

von Pedró-Rosa, L. | Buckner, F. | Ranade, R. | +13

ErratumIn: J Biomol Screen. 2016 Jul;21(6):653. - PMID 27189835

4

Structures of Trypanosoma brucei methionyl-tRNA synthetase with urea-based inhibitors provide guidance for drug design against sleeping sickness

enthalten in: PLoS neglected tropical diseases | 2014

von Koh, C. | Kim, J. | Wetzel, A. | +10

5

Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection

enthalten in: Structure (London, England : 1993) | 2012

von Koh, C. | Kim, J. | Shibata, S. | +8

6

Urea-based inhibitors of Trypanosoma brucei methionyl-tRNA synthetase : selectivity and in vivo characterization

enthalten in: Journal of medicinal chemistry | 2012

von Shibata, S. | Gillespie, J. | Ranade, R. | +8

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