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PubPharm (33)
1
Cross-species drug metabolism and impact of metabolic stability testing under anaerobic condition on predicting pharmacokinetics of keto-enol containing compound in humans
enthalten in:
Drug metabolism and pharmacokinetics
| 2024
von
Kanazu, T.
|
Tamada, J.
|
Kume, S.
| +1
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2
Improved Predictability of Hepatic Clearance with Optimal pH for Acyl-Glucuronidation in Liver Microsomes
enthalten in:
Journal of pharmaceutical sciences
| 2022
von
Mizutare, T.
|
Sanoh, S.
|
Kanazu, T.
| +2
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3
Human mass balance, metabolism, and cytochrome P450 phenotyping of lusutrombopag
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2021
von
Kawachi, T.
|
Ninomiya, M.
|
Katsube, T.
| +2
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4
Discovery of Atabecestat (JNJ-54861911) : A Thiazine-Based β-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b/3 EARLY Clinical Trial
enthalten in:
Journal of medicinal chemistry
| 2021
von
Koriyama, Y.
|
Hori, A.
|
Ito, H.
| +19
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5
Human mass balance, metabolism, and cytochrome P450 phenotyping of lusutrombopag
enthalten in:
Xenobiotica
| 2021
von
Kawachi, T.
|
Ninomiya, M.
|
Katsube, T.
| +2
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6
The Novel In Vitro Method to Calculate Tissue-to-Plasma Partition Coefficient in Humans for Predicting Pharmacokinetic Profiles by Physiologically-Based Pharmacokinetic Model With High Predictability
enthalten in:
Journal of pharmaceutical sciences
| 2020
von
Mayumi, K.
|
Tachibana, M.
|
Yoshida, M.
| +3
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7
Successful Prediction of Human Pharmacokinetics After Oral Administration by Optimized Physiologically Based Pharmacokinetics Approach and Permeation Assay Using Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Cells
enthalten in:
Journal of pharmaceutical sciences
| 2020
von
Mayumi, K.
|
Akazawa, T.
|
Kanazu, T.
| +2
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8
Metabolite profiling of guanfacine in plasma and urine of healthy Japanese subjects after oral administration of guanfacine extended-release tablets
enthalten in:
Biopharmaceutics & drug disposition
| 2019
von
Inoue, Y.
|
Morita, H.
|
Nozawa, K.
| +1
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9
Metabolite profiling of guanfacine in plasma and urine of healthy Japanese subjects after oral administration of guanfacine extended‐release tablets
enthalten in:
Biopharmaceutics & Drug Disposition
| 2019
von
Inoue, Y.
|
Morita, H.
|
Nozawa, K.
| +1
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10
Application of Intestinal Epithelial Cells Differentiated from Human Induced Pluripotent Stem Cells for Studies of Prodrug Hydrolysis and Drug Absorption in the Small Intestine
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2018
von
Akazawa, T.
|
Yoshida, S.
|
Ohnishi, S.
| +3
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Xenobiotica
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Xenobiotica; the fate of foreign compounds in b...
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18
Journal Article
5
Research Support, Non-U.S. Gov't
4
Acids, Carbocyclic
4
Cyclopentanes
4
Guanidines
4
QW7Y7ZR15U
4
peramivir
3
Antiviral Agents
3
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3
S-777469
3
human mass balance study
3
metabolite profiling
2
7S5I7G3JQL
2
CNR2 protein, human
2
Clinical Trial, Phase I
2
Cytochrome P-450 CYP3A
2
Dexamethasone
2
EC 1.14.14.1
2
EC 2.4.1.17
2
Glucuronosyltransferase
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Erscheinungszeitraum
32
2000-
1
1900-1999
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24
Englisch
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