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PubPharm (6)
1
Selection of the candidate compound at an early stage of new drug development : retrospective pharmacokinetic and metabolic evaluations of valsartan using common marmosets
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Matsumoto, S.
|
Uehara, S.
|
Kamimura, H.
| +7
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2
Selection of the candidate compound at an early stage of new drug development: retrospective pharmacokinetic and metabolic evaluations of valsartan using common marmosets
enthalten in:
Xenobiotica
| 2022
von
Matsumoto, S.
|
Uehara, S.
|
Kamimura, H.
| +7
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3
A novel Css-MRTpo approach to simulate oral plasma concentration-time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite in humans using chimeric mice with humanized livers
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2020
von
Kamimura, H.
|
Uehara, S.
|
Suemizu, H.
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4
A novel Css-MRTpo approach to simulate oral plasma concentration–time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite in humans using chimeric mice with humanized livers
enthalten in:
Xenobiotica
| 2020
von
Kamimura, H.
|
Uehara, S.
|
Suemizu, H.
Wird geladen...
5
Simulation of human plasma concentration-time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite using humanized chimeric mice and semi-physiological pharmacokinetic modeling
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2017
von
Kamimura, H.
|
Ito, S.
|
Chijiwa, H.
| +9
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6
Assessment of chimeric mice with humanized livers in new drug development : generation of pharmacokinetics, metabolism and toxicity data for selecting the final candidate compound
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2016
von
Kamimura, H.
|
Ito, S.
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1
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Thema: MIST guidance
Medienart
6
Aufsätze
6
E-Artikel
6
E-Ressourcen
Zeitschriftentitel
4
Xenobiotica; the fate of foreign compounds in b...
2
Xenobiotica
Thema
MIST guidance
4
Chimeric mouse
4
Journal Article
4
humanized liver
3
disproportionate metabolite
2
Allometry
2
Benzofurans
2
Css-MRT approach
2
EC 2.7.1.2
2
Glucokinase
2
N,N-dimethyl-5-((2-methyl-6-((5-methylpyrazin-2...
2
PK prediction
2
Pharmaceutical Preparations
2
Pyrimidines
2
common marmoset
2
compound optimisation
2
metabolic profile
2
oral administration
2
prediction
2
total clearance
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Erscheinungszeitraum
4
2020-
2
2010-2019
Erscheinungsjahr(e)
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6
Englisch
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