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topic_facet:"EC 1.14.14.1"
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PubPharm (7)
1
An improved TK-NOG mouse as a novel platform for humanized liver that overcomes limitations in both male and female animals
enthalten in:
Drug metabolism and pharmacokinetics
| 2022
von
Uehara, S.
|
Higuchi, Y.
|
Yoneda, N.
| +10
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2
Human total clearance values and volumes of distribution of typical human cytochrome P450 2C9/19 substrates predicted by single-species allometric scaling using pharmacokinetic data sets from common marmosets genotyped for P450 2C19
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2021
von
Matsumoto, S.
|
Uehara, S.
|
Kamimura, H.
| +6
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3
Murine Cyp3a knockout chimeric mice with humanized liver : prediction of the metabolic profile of nefazodone in humans
enthalten in:
Biopharmaceutics & drug disposition
| 2016
von
Nakada, N.
|
Kawamura, A.
|
Kamimura, H.
| +8
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4
Development of Murine Cyp3a Knockout Chimeric Mice with Humanized Liver
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2015
von
Kato, K.
|
Ohbuchi, M.
|
Hamamura, S.
| +9
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5
Time-dependent inhibitory effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.0(4.9)]octacos-18-ene-2,3,10,16-tetrone (FK1706), a novel nonimmunosuppressive immunophilin ligand, on CYP3A4/5 activity in humans in vivo and in vitro
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2010
von
Minematsu, T.
|
Lee, J.
|
Zha, J.
| +6
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6
Elucidation of the effects of the CYP1A2 deficiency polymorphism in the metabolism of 4-cyclohexyl-1-ethyl-7-methylpyrido[2,3-d]pyrimidine-2-(1h)-one (YM-64227), a phosphodiesterase type 4 inhibitor, and its metabolites in dogs
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2006
von
Tenmizu, D.
|
Noguchi, K.
|
Kamimura, H.
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7
The canine CYP1A2 deficiency polymorphism dramatically affects the pharmacokinetics of 4-cyclohexyl-1-ethyl-7-methylpyrido[2,3-D]-pyrimidine-2-(1H)-one (YM-64227), a phosphodiesterase type 4 inhibitor
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2006
von
Tenmizu, D.
|
Noguchi, K.
|
Kamimura, H.
| +2
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Thema: EC 1.14.14.1
Medienart
7
Aufsätze
5
E-Artikel
5
E-Ressourcen
2
Gedruckte Aufsätze
Zeitschriftentitel
4
Drug metabolism and disposition: the biological...
1
Biopharmaceutics & drug disposition
1
Drug metabolism and pharmacokinetics
1
Xenobiotica; the fate of foreign compounds in b...
Thema
EC 1.14.14.1
7
Journal Article
4
Cytochrome P-450 CYP3A
2
3',5'-Cyclic-AMP Phosphodiesterases
2
4-cyclohexyl-1-ethyl-7-methylpyrido(2,3-d)pyrim...
2
Cyclic Nucleotide Phosphodiesterases, Type 4
2
Cyclohexanes
2
Cytochrome P-450 CYP1A2
2
EC 3.1.4.17
2
Midazolam
2
Pyrimidines
2
R60L0SM5BC
1
1HM943223R
1
59H4FCV1TF
1
5Q7ZVV76EI
1
604-59-1
1
9035-51-2
1
Albumins
1
Allometry
1
Antibodies, Monoclonal
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Erscheinungszeitraum
2
2020-
3
2010-2019
2
2000-2009
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7
Englisch
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