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topic_facet:"Allometry"
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PubPharm (5)
1
Selection of the candidate compound at an early stage of new drug development : retrospective pharmacokinetic and metabolic evaluations of valsartan using common marmosets
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2022
von
Matsumoto, S.
|
Uehara, S.
|
Kamimura, H.
| +7
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2
Selection of the candidate compound at an early stage of new drug development: retrospective pharmacokinetic and metabolic evaluations of valsartan using common marmosets
enthalten in:
Xenobiotica
| 2022
von
Matsumoto, S.
|
Uehara, S.
|
Kamimura, H.
| +7
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3
Human total clearance values and volumes of distribution of typical human cytochrome P450 2C9/19 substrates predicted by single-species allometric scaling using pharmacokinetic data sets from common marmosets genotyped for P450 2C19
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2021
von
Matsumoto, S.
|
Uehara, S.
|
Kamimura, H.
| +6
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4
Human total clearance values and volumes of distribution of typical human cytochrome P450 2C9/19 substrates predicted by single-species allometric scaling using pharmacokinetic data sets from common marmosets genotyped forP450 2C19
enthalten in:
Xenobiotica
| 2021
von
Matsumoto, S.
|
Uehara, S.
|
Kamimura, H.
| +6
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5
Empirical and theoretical approaches for the prediction of human hepatic clearance using chimeric mice with humanised liver : the use of physiologically based scaling, a novel solution for potential overprediction due to coexisting mouse metabolism
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2021
von
Matsumoto, S.
|
Kamimura, H.
|
Nishiwaki, M.
| +3
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Thema: Allometry
Medienart
5
Aufsätze
5
E-Artikel
5
E-Ressourcen
Zeitschriftentitel
3
Xenobiotica; the fate of foreign compounds in b...
2
Xenobiotica
Thema
Allometry
5
prediction
3
Journal Article
3
metabolic clearance
2
CYP2C substrate
2
MIST guidance
2
Pharmaceutical Preparations
2
common marmoset
2
compound optimisation
2
distribution volume
2
metabolic profile
2
total clearance
2
volume of distribution
1
11128-99-7
1
5Q7ZVV76EI
1
80M03YXJ7I
1
Angiotensin II
1
Antihypertensive Agents
1
Cytochrome P-450 CYP2C19
1
Cytochrome P-450 CYP2C9
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Erscheinungszeitraum
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2022
3
2021
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Englisch
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