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PubPharm (17)
1
Development of Murine Cyp3a Knockout Chimeric Mice with Humanized Liver
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2015
von
Kato, K.
|
Ohbuchi, M.
|
Hamamura, S.
| +9
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2
Formation of the accumulative human metabolite and human-specific glutathione conjugate of diclofenac in TK-NOG chimeric mice with humanized livers
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2015
von
Kamimura, H.
|
Ito, S.
|
Nozawa, K.
| +7
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3
Time-dependent inhibitory effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.0(4.9)]octacos-18-ene-2,3,10,16-tetrone (FK1706), a novel nonimmunosuppressive immunophilin ligand, on CYP3A4/5 activity in humans in vivo and in vitro
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2010
von
Minematsu, T.
|
Lee, J.
|
Zha, J.
| +6
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4
Characterization of human organic cation transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-mediated transport of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small molecule survivin suppressant
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2010
von
Minematsu, T.
|
Iwai, M.
|
Umehara, K.
| +2
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5
Investigation of long-term retention of unchanged (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, a novel "funny" If current channel inhibitor, and its metabolites in the eyeball and thoracic aorta of rats
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2009
von
Umehara, K.
|
Nakada, N.
|
Noguchi, K.
| +3
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6
Involvement of human organic cation transporter 1 in the hepatic uptake of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel, small molecule survivin suppressant
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2009
von
Iwai, M.
|
Minematsu, T.
|
Narikawa, S.
| +2
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7
Identification of human metabolites of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel If channel inhibitor, and investigation of the transporter-mediated renal and hepatic excretion of these metabolites
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2009
von
Umehara, K.
|
Shirai, N.
|
Iwatsubo, T.
| +3
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8
Relationship between exposure of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a "funny" if current channel inhibitor, and heart rate reduction in tachycardia-induced beagle dogs
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2009
von
Umehara, K.
|
Wada, K.
|
Noguchi, K.
| +3
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9
Carrier-mediated uptake of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small-molecule survivin suppressant, into human solid tumor and lymphoma cells
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2009
von
Minematsu, T.
|
Iwai, M.
|
Sugimoto, K.
| +4
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10
Role of organic anion transporters in the pharmacokinetics of zonampanel, an alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, in rats
enthalten in:
Drug metabolism and disposition: the biological fate of chemicals
| 2008
von
Minematsu, T.
|
Hashimoto, T.
|
Aoki, T.
| +2
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Zeitschrift: Drug metabolism and disposition: the biological fate of chemicals
Medienart
17
Aufsätze
11
E-Artikel
11
E-Ressourcen
6
Gedruckte Aufsätze
Zeitschriftentitel
Drug metabolism and disposition: the biological...
Thema
17
Journal Article
5
Imidazoles
4
Benzamides
4
EC 1.14.14.1
4
EC 2.4.1.17
4
Enzyme Inhibitors
4
Glucuronosyltransferase
4
Isoquinolines
4
YM 758
3
BIRC5 protein, human
3
Comparative Study
3
Inhibitor of Apoptosis Proteins
3
Microtubule-Associated Proteins
3
Naphthoquinones
3
Organic Anion Transporters
3
Organic Cation Transporter 1
3
Survivin
3
UZ77T1VFBM
3
sepantronium
2
11G3FV7PG7
Alle anzeigen ...
weniger ...
Erscheinungszeitraum
4
2010-2019
13
2000-2009
Erscheinungsjahr(e)
Von:
Bis:
Sprache
17
Englisch
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