Suchergebnisse - "Kamimura, Hidetaka"

PubPharm (71)

1

Murine Cyp3a knockout chimeric mice with humanized liver: prediction of the metabolic profile of nefazodone in humans

enthalten in: Biopharmaceutics & drug disposition | 2016

von Kakuni, M. | Kawamura, A. | Kazuki, Y. | +8

2

Assessment of chimeric mice with humanized livers in new drug development: generation of pharmacokinetics, metabolism and toxicity data for selecting the final candidate compound

enthalten in: Xenobiotica | 2016

von Kamimura, H. | Ito, S.

3

Simulation of human plasma concentration–time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite using humanized chimeric mice and semi-physiological pharmacokinetic modeling

enthalten in: Xenobiotica | 2016

von Kamimura, H. | Ito, S. | Chijiwa, H. | +9

4

Time-Dependent Inhibitory Effects of (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04.9]octacos-18-ene-2,3,10,16-tetrone (FK1706), a Novel Nonimmunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in Vitro

enthalten in: Drug metabolism and disposition | 2010

von Minematsu, T. | Lee, J. | Zha, J. | +6

5

21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-(E)-2-[(1R,3R,4R)-4-hydroxy Time-Dependent Inhibitory Effects of (1R,9S,12S,13R,14S,17R,18E, tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04.9] -octacos-18-ene-2,3,10,16-tetrone (FK1706), a Novel Nonimmunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in Vitro.

enthalten in: Drug metabolism and disposition | 2010

von Minematsu, T. | Lee, J. | Zha, J. | +6

6

Advertising Sin and Sickness: The Politics of Alcohol and Tobacco Marketing 1950–1990 (review)

enthalten in: Bulletin of the history of medicine | 2009

von Minematsu, T. | Iwai, M. | Umehara, K. | +2

7

Carrier-Mediated Uptake of 1-(2-Methoxyethyl) -2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl) -4,9-dihydro-1H-naphtho(2,3-d)imidazolium Bromide (YM155 Monobromide), a Novel Small-Molecule Survivin Suppressant, into Human Solid Tumor and Lymphoma Cells.

enthalten in: Drug metabolism and disposition | 2009

von Minematsu, T. | Iwai, M. | Sugimoto, K. | +4

8

Relationship between Exposure of (-)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinol- ine-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a "Funny" If Current Channel Inhibitor, and Heart Rate Reduction in Tachycardia-Induced Beagle Dogs

enthalten in: Drug metabolism and disposition | 2009

von Umehara, K. | Wada, K. | Noguchi, K. | +3

9

Identification of Human Metabolites of (-)-N-(2-((R)-3-(6,7- Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino) ethyl)-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, and Investigation of the Transporter-Mediated Renal and Hepatic Excretion of These Metabolites.

enthalten in: Drug metabolism and disposition | 2009

von Umehara, K. | Shirai, N. | Iwatsubo, T. | +3

10

Involvement of Human Organic Cation Transporter 1 in the Hepatic Upt

enthalten in: Drug metabolism and disposition | 2009

von Iwai, M. | Minematsu, T. | Narikawa, S. | +2

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