Suchergebnisse - "Jones, Lyn"

PubPharm (7)

1

Quantifying drug-target engagement in live cells using sulfonyl fluoride chemical probes

enthalten in: Methods in enzymology | 2019

von Jones, L. | Xu, H. | Fadeyi, O.

2

Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA)

enthalten in: Journal of medicinal chemistry | 2017

von Gopalsamy, A. | Narayanan, A. | Liu, S. | +16

3

In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS : Context-specific modulation of SMN transcript levels

enthalten in: PloS one | 2017

von Cherry, J. | DiDonato, C. | Androphy, E. | +22

4

Selectivity Determination of a Small Molecule Chemical Probe Using Protein Microarray and Affinity Capture Techniques

enthalten in: ACS combinatorial science | 2016

von Hett, E. | Kyne, R. | Gopalsamy, A. | +5

5

Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells

enthalten in: Organic & biomolecular chemistry | 2016

von Xu, H. | Gopalsamy, A. | Hett, E. | +5

6

A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS

enthalten in: Molecular bioSystems | 2015

von Xu, H. | Hett, E. | Gopalsamy, A. | +9

7

Rational targeting of active-site tyrosine residues using sulfonyl fluoride probes

enthalten in: ACS chemical biology | 2015

von Hett, E. | Xu, H. | Geoghegan, K. | +10

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