Suchergebnisse - "Jansson, Patric J"

PubPharm (108)

51

Novel Mechanism of Cytotoxicity for the Selective Selenosemicarbazone, 2-Acetylpyridine 4,4-Dimethyl-3-selenosemicarbazone (Ap44mSe) : Lysosomal Membrane Permeabilization

enthalten in: Journal of medicinal chemistry | 2016

von Al-Eisawi, Z. | Stefani, C. | Jansson, P. | +11

52

Novel Mechanism of Cytotoxicity for the Selective Selenosemicarbazone, 2-Acetylpyridine 4,4-Dimethyl-3-selenosemicarbazone (Ap44mSe): Lysosomal Membrane Permeabilization

enthalten in: Journal of medicinal chemistry | 2016

von Arvind, A. | Sharpe, P. | Richardson, D. | +11

53

Zinc(II)-Thiosemicarbazone Complexes Are Localized to the Lysosomal Compartment Where They Transmetallate with Copper Ions to Induce Cytotoxicity

enthalten in: Journal of medicinal chemistry | 2016

von Stacy, A. | Palanimuthu, D. | Bernhardt, P. | +3

54

Turning the gun on cancer: Utilizing lysosomal P-glycoprotein as a new strategy to overcome multi-drug resistance

enthalten in: Free radical biology & medicine | 2016

von Seebacher, N. | Lane, D. | Richardson, D. | +1

55

Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase

enthalten in: Biochemical pharmacology | 2016

von Merlot, A. | Shafie, N. | Yu, Y. | +7

56

Structure-Activity Relationships of Di-2-pyridylketone, 2-Benzoylpyridine, and 2-Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance

enthalten in: Journal of medicinal chemistry | 2016

von Stacy, A. | Palanimuthu, D. | Bernhardt, P. | +3

57

Identification of differential anti-neoplastic activity of copper bis(thiosemicarbazones) that is mediated by intracellular reactive oxygen species generation and lysosomal membrane permeabilization

enthalten in: Journal of inorganic biochemistry | 2015

von Stefani, C. | Al-Eisawi, Z. | Jansson, P. | +2

58

The molecular effect of metastasis suppressors on Src signaling and tumorigenesis : new therapeutic targets

enthalten in: Oncotarget | 2015

von Liu, W. | Kovacevic, Z. | Peng, Z. | +12

59

The renaissance of polypharmacology in the development of anti-cancer therapeutics : Inhibition of the "Triad of Death" in cancer by Di-2-pyridylketone thiosemicarbazones

enthalten in: Pharmacological research | 2015

von Jansson, P. | Kalinowski, D. | Lane, D. | +6

60

Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes multidrug resistance by a novel mechanism involving the hijacking of lysosomal P-glycoprotein (Pgp)

enthalten in: The Journal of biological chemistry | 2015

von Jansson, P. | Yamagishi, T. | Arvind, A. | +7