Suchergebnisse - "Jansson, Patric J"

PubPharm (33)

1

Novel Mechanism of Cytotoxicity for the Selective Selenosemicarbazone, 2-Acetylpyridine 4,4-Dimethyl-3-selenosemicarbazone (Ap44mSe): Lysosomal Membrane Permeabilization

enthalten in: Journal of medicinal chemistry | 2016

von Arvind, A. | Sharpe, P. | Richardson, D. | +11

2

Zinc(II)-Thiosemicarbazone Complexes Are Localized to the Lysosomal Compartment Where They Transmetallate with Copper Ions to Induce Cytotoxicity

enthalten in: Journal of medicinal chemistry | 2016

von Stacy, A. | Palanimuthu, D. | Bernhardt, P. | +3

3

Turning the gun on cancer: Utilizing lysosomal P-glycoprotein as a new strategy to overcome multi-drug resistance

enthalten in: Free radical biology & medicine | 2016

von Seebacher, N. | Lane, D. | Richardson, D. | +1

4

Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase

enthalten in: Biochemical pharmacology | 2016

von Merlot, A. | Shafie, N. | Yu, Y. | +7

5

Structure-Activity Relationships of Di-2-pyridylketone, 2-Benzoylpyridine, and 2-Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance

enthalten in: Journal of medicinal chemistry | 2016

von Stacy, A. | Palanimuthu, D. | Bernhardt, P. | +3

6

IRON METABOLISM AND AUTOPHAGY : A POORLY EXPLORED RELATIONSHIP THAT HAS IMPORTANT CONSEQUENCES FOR HEALTH AND DISEASE

enthalten in: Nagoya journal of medical science | 2015

von Krishan, S. | Jansson, P. | Gutierrez, E. | +3

7

Identification of differential anti-neoplastic activity of copper bis(thiosemicarbazones) that is mediated by intracellular reactive oxygen species generation and lysosomal membrane permeabilization

enthalten in: Journal of inorganic biochemistry | 2015

von Stefani, C. | Al-Eisawi, Z. | Jansson, P. | +2

8

The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the "Triad of Death" in cancer by Di-2-pyridylketone thiosemicarbazones

enthalten in: Pharmacological research | 2015

von Jansson, P. | Kalinowski, D. | Lane, D. | +6

9

Gene of the month: BECN1

enthalten in: Journal of clinical pathology | 2014

von Sahni, S. | Merlot, A. | Krishan, S. | +2

10

Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy

enthalten in: Reviews on cancer | 2014

von Fang, B. | Kovačević, �. | Park, K. | +5