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topic_facet:"Antineoplastic Agents"
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PubPharm (44)
1
Preclinical Characterization and Phase I Study of an Anti-HER2-TLR7 Immune-Stimulator Antibody Conjugate in Patients with HER2+ Malignancies
enthalten in:
Cancer immunology research
| 2022
von
Janku, F.
|
Han, S.
|
Doi, T.
| +15
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2
First-in-human study of IM156, a novel potent biguanide oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced solid tumors
enthalten in:
Investigational new drugs
| 2022
von
Janku, F.
|
Beom, S.
|
Moon, Y.
| +14
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3
First-in-human evaluation of the novel mitochondrial complex I inhibitor ASP4132 for treatment of cancer
enthalten in:
Investigational new drugs
| 2021
von
Janku, F.
|
LoRusso, P.
|
Mansfield, A.
| +6
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4
Phase I Assessment of Safety and Therapeutic Activity of BAY1436032 in Patients with IDH1-Mutant Solid Tumors
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2021
von
Wick, A.
|
Bähr, O.
|
Schuler, M.
| +28
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5
Ivosidenib in Isocitrate Dehydrogenase 1-Mutated Advanced Glioma
enthalten in:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
| 2020
von
Mellinghoff, I.
|
Ellingson, B.
|
Touat, M.
| +18
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6
Safety and activity of ivosidenib in patients with IDH1-mutant advanced cholangiocarcinoma : a phase 1 study
enthalten in:
The lancet. Gastroenterology & hepatology
| 2019
von
Lowery, M.
|
Burris, H.
|
Janku, F.
| +19
CommentIn: Lancet Gastroenterol Hepatol. 2019 Sep;4(9):661-662. - PMID 31300361
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7
Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants
enthalten in:
Cancer cell
| 2019
von
Smith, B.
|
Kaufman, M.
|
Lu, W.
| +26
CommentIn: Nat Rev Cancer. 2019 Jul;19(7):370. - PMID 31201392
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8
Phase I study of the combination of crizotinib (as a MET inhibitor) and dasatinib (as a c-SRC inhibitor) in patients with advanced cancer
enthalten in:
Investigational new drugs
| 2018
von
Kato, S.
|
Jardim, D.
|
Johnson, F.
| +16
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9
Antiangiogenesis and gene aberration-related therapy may improve overall survival in patients with concurrent KRAS and TP53 hotspot mutant cancer
enthalten in:
Oncotarget
| 2017
von
Wang, Z.
|
Piha-Paul, S.
|
Janku, F.
| +14
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10
Circulating tumor DNA-From bench to bedside
enthalten in:
Current problems in cancer
| 2017
von
Lim, J.
|
Janku, F.
|
Yap, T.
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Thema: Antineoplastic Agents
Medienart
44
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44
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Zeitschriftentitel
7
Oncotarget
5
Clinical cancer research : an official journal ...
5
Investigational new drugs
4
Journal of clinical oncology : official journal...
3
Discovery medicine
3
Molecular cancer therapeutics
2
Nature reviews. Clinical oncology
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The lancet. Gastroenterology & hepatology
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Thema
Antineoplastic Agents
43
Journal Article
16
Research Support, Non-U.S. Gov't
14
Protein Kinase Inhibitors
14
Research Support, N.I.H., Extramural
11
Clinical Trial, Phase I
10
EC 2.7.10.1
9
EC 2.7.11.1
9
Review
8
TOR Serine-Threonine Kinases
6
EC 2.7.1.137
6
Proto-Oncogene Proteins c-akt
5
Case Reports
5
Class I Phosphatidylinositol 3-Kinases
5
Multicenter Study
5
PIK3CA protein, human
4
Angiogenesis Inhibitors
4
EC 1.1.1.41
4
EC 3.6.5.2
4
ErbB Receptors
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Erscheinungszeitraum
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2020-
39
2010-2019
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