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topic_facet:"fimH protein, E coli"
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PubPharm (10)
1
A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis
enthalten in:
PLoS pathogens
| 2021
von
McLellan, L.
|
McAllaster, M.
|
Kim, A.
| +10
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2
Rational design strategies for FimH antagonists : new drugs on the horizon for urinary tract infection and Crohn's disease
enthalten in:
Expert opinion on drug discovery
| 2017
von
Mydock-McGrane, L.
|
Hannan, T.
|
Janetka, J.
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3
Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist
enthalten in:
Nature
| 2017
von
Spaulding, C.
|
Klein, R.
|
Ruer, S.
| +10
CommentIn: Nature. 2017 Jun 22;546(7659):479-480. - PMID 28614303
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4
Antivirulence Isoquinolone Mannosides : Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI
enthalten in:
ChemMedChem
| 2016
von
Jarvis, C.
|
Han, Z.
|
Kalas, V.
| +9
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5
Mannose-derived FimH antagonists : a promising anti-virulence therapeutic strategy for urinary tract infections and Crohn's disease
enthalten in:
Expert opinion on therapeutic patents
| 2016
von
Mydock-McGrane, L.
|
Cusumano, Z.
|
Janetka, J.
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6
A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131
enthalten in:
The Journal of infectious diseases
| 2013
von
Totsika, M.
|
Kostakioti, M.
|
Hannan, T.
| +5
CommentIn: J Urol. 2014 Jul;192(1):276. - PMID 25629130
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7
Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice
enthalten in:
Antimicrobial agents and chemotherapy
| 2012
von
Guiton, P.
|
Cusumano, C.
|
Kline, K.
| +6
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8
Lead optimization studies on FimH antagonists : discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides
enthalten in:
Journal of medicinal chemistry
| 2012
von
Han, Z.
|
Pinkner, J.
|
Ford, B.
| +7
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9
Treatment and prevention of urinary tract infection with orally active FimH inhibitors
enthalten in:
Science translational medicine
| 2011
von
Cusumano, C.
|
Pinkner, J.
|
Han, Z.
| +6
CommentIn: Nat Rev Urol. 2012 Jan;9(1):6. - PMID 22200833
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10
Structure-based drug design and optimization of mannoside bacterial FimH antagonists
enthalten in:
Journal of medicinal chemistry
| 2010
von
Han, Z.
|
Pinkner, J.
|
Ford, B.
| +8
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1
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Thema: fimH protein, E coli
Medienart
10
Aufsätze
10
E-Artikel
10
E-Ressourcen
Zeitschriftentitel
2
Journal of medicinal chemistry
1
Antimicrobial agents and chemotherapy
1
ChemMedChem
1
Expert opinion on drug discovery
1
Expert opinion on therapeutic patents
1
Nature
1
PLoS pathogens
1
Science translational medicine
1
The Journal of infectious diseases
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Thema
10
147680-16-8
10
Adhesins, Escherichia coli
10
Fimbriae Proteins
10
Journal Article
fimH protein, E coli
9
Research Support, N.I.H., Extramural
7
Mannosides
6
Anti-Bacterial Agents
6
Research Support, Non-U.S. Gov't
3
FimH
3
mannoside
2
Crohn’s disease
2
Research Support, American Recovery and Reinves...
2
Review
2
lectin
2
urinary tract infection
1
8064-90-2
1
AIEC
1
Biphenyl Compounds
1
Desmoglein 2
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Erscheinungszeitraum
1
2020-
9
2010-2019
Erscheinungsjahr(e)
Von:
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Sprache
10
Englisch
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