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topic_facet:"Anti-Bacterial Agents"
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PubPharm (8)
1
Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection
enthalten in:
Proceedings of the National Academy of Sciences of the United States of America
| 2018
von
Kalas, V.
|
Hibbing, M.
|
Maddirala, A.
| +6
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2
Rational design strategies for FimH antagonists : new drugs on the horizon for urinary tract infection and Crohn's disease
enthalten in:
Expert opinion on drug discovery
| 2017
von
Mydock-McGrane, L.
|
Hannan, T.
|
Janetka, J.
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3
Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections
enthalten in:
Journal of medicinal chemistry
| 2016
von
Mydock-McGrane, L.
|
Cusumano, Z.
|
Han, Z.
| +10
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4
Antivirulence Isoquinolone Mannosides : Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI
enthalten in:
ChemMedChem
| 2016
von
Jarvis, C.
|
Han, Z.
|
Kalas, V.
| +9
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5
Mannose-derived FimH antagonists : a promising anti-virulence therapeutic strategy for urinary tract infections and Crohn's disease
enthalten in:
Expert opinion on therapeutic patents
| 2016
von
Mydock-McGrane, L.
|
Cusumano, Z.
|
Janetka, J.
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6
A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131
enthalten in:
The Journal of infectious diseases
| 2013
von
Totsika, M.
|
Kostakioti, M.
|
Hannan, T.
| +5
CommentIn: J Urol. 2014 Jul;192(1):276. - PMID 25629130
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7
Treatment and prevention of urinary tract infection with orally active FimH inhibitors
enthalten in:
Science translational medicine
| 2011
von
Cusumano, C.
|
Pinkner, J.
|
Han, Z.
| +6
CommentIn: Nat Rev Urol. 2012 Jan;9(1):6. - PMID 22200833
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8
Structure-based drug design and optimization of mannoside bacterial FimH antagonists
enthalten in:
Journal of medicinal chemistry
| 2010
von
Han, Z.
|
Pinkner, J.
|
Ford, B.
| +8
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1
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Thema: Anti-Bacterial Agents
Medienart
8
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Journal of medicinal chemistry
1
ChemMedChem
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Anti-Bacterial Agents
8
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7
Adhesins, Escherichia coli
6
147680-16-8
6
Fimbriae Proteins
6
Research Support, N.I.H., Extramural
6
fimH protein, E coli
5
Mannosides
3
FimH
3
mannoside
3
urinary tract infection
2
Crohn’s disease
2
Research Support, Non-U.S. Gov't
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lectin
1
AIEC
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E. coli ST131
1
E. coli bacteria
1
FmlH protein, E coli
1
Galactosides
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