Suchergebnisse - "Janetka, James W"

PubPharm (13)

1

Discovery of Orally Bioavailable FmlH Lectin Antagonists as Treatment for Urinary Tract Infections

enthalten in: Journal of medicinal chemistry | 2024

von Maddirala, A. | Tamadonfar, K. | Pinkner, J. | +3

2

A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis

enthalten in: PLoS pathogens | 2021

von McLellan, L. | McAllaster, M. | Kim, A. | +10

3

Biphenyl Gal and GalNAc FmlH Lectin Antagonists of Uropathogenic E. coli (UPEC) : Optimization through Iterative Rational Drug Design

enthalten in: Journal of medicinal chemistry | 2019

von Maddirala, A. | Klein, R. | Pinkner, J. | +3

4

Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection

enthalten in: Proceedings of the National Academy of Sciences of the United States of America | 2018

von Kalas, V. | Hibbing, M. | Maddirala, A. | +6

5

Rational design strategies for FimH antagonists : new drugs on the horizon for urinary tract infection and Crohn's disease

enthalten in: Expert opinion on drug discovery | 2017

von Mydock-McGrane, L. | Hannan, T. | Janetka, J.

6

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

enthalten in: Nature | 2017

von Spaulding, C. | Klein, R. | Ruer, S. | +10

CommentIn: Nature. 2017 Jun 22;546(7659):479-480. - PMID 28614303

7

Antivirulence Isoquinolone Mannosides : Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI

enthalten in: ChemMedChem | 2016

von Jarvis, C. | Han, Z. | Kalas, V. | +9

8

Mannose-derived FimH antagonists : a promising anti-virulence therapeutic strategy for urinary tract infections and Crohn's disease

enthalten in: Expert opinion on therapeutic patents | 2016

von Mydock-McGrane, L. | Cusumano, Z. | Janetka, J.

9

A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131

enthalten in: The Journal of infectious diseases | 2013

von Totsika, M. | Kostakioti, M. | Hannan, T. | +5

CommentIn: J Urol. 2014 Jul;192(1):276. - PMID 25629130

10

Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice

enthalten in: Antimicrobial agents and chemotherapy | 2012

von Guiton, P. | Cusumano, C. | Kline, K. | +6