Suchergebnisse - "Hu, Yongzhou"

PubPharm (22)

1

Discovery of N-((3S,4S)-4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1H-pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity

enthalten in: Journal of medicinal chemistry | 2021

von Che, J. | Dai, X. | Gao, J. | +13

2

Recent advances in FLT3 inhibitors for acute myeloid leukemia

enthalten in: Future medicinal chemistry | 2020

von Tong, L. | Li, X. | Hu, Y. | +1

3

Discovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors

enthalten in: European journal of medicinal chemistry | 2019

von Zhan, W. | Che, J. | Xu, L. | +7

4

Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino)pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies

enthalten in: European journal of medicinal chemistry | 2019

von Tong, L. | Song, P. | Jiang, K. | +10

5

Design, synthesis and biological evaluation of novel benzothiadiazine derivatives as potent PI3Kδ-selective inhibitors for treating B-cell-mediated malignancies

enthalten in: European journal of medicinal chemistry | 2019

von Ma, X. | Wei, J. | Wang, C. | +3

6

Design, synthesis, and biological study of 4-[(2-nitroimidazole-1H-alkyloxyl)aniline]-quinazolines as EGFR inhibitors exerting cytotoxicities both under normoxia and hypoxia

enthalten in: Drug design, development and therapy | 2019

von Cheng, W. | Wang, S. | Yang, Z. | +2

7

Discovery of a series of N-(5-(quinolin-6-yl)pyridin-3-yl)benzenesulfonamides as PI3K/mTOR dual inhibitors

enthalten in: European journal of medicinal chemistry | 2017

von Zhang, J. | Lv, X. | Ma, X. | +1

8

Discovery of 4-chloro-3-(5-(pyridin-3-yl)-1,2,4-oxadiazole-3-yl)benzamides as novel RET kinase inhibitors

enthalten in: Bioorganic & medicinal chemistry letters | 2016

von Han, M. | Li, S. | Ai, J. | +4

9

Design, synthesis and biological evaluation of pyrazol-furan carboxamide analogues as novel Akt kinase inhibitors

enthalten in: European journal of medicinal chemistry | 2016

von Zhan, W. | Xu, L. | Dong, X. | +8

10

Discovery of novel quinoline-based mTOR inhibitors via introducing intra-molecular hydrogen bonding scaffold (iMHBS) : The design, synthesis and biological evaluation

enthalten in: Bioorganic & medicinal chemistry | 2015

von Ma, X. | Lv, X. | Qiu, N. | +3