Suchergebnisse - "Hu, Yongzhou"

PubPharm (153)

1

Discovery of seneciobipyrrolidine derivatives for the amelioration of glucose homeostasis disorders through 4E-BP1/Akt/AMPK signaling activation

enthalten in: European journal of medicinal chemistry | 2022

von Che, J. | Ma, C. | Lu, J. | +9

2

Discovery of N-((3S,4S)-4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1H-pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity

enthalten in: Journal of medicinal chemistry | 2021

von Che, J. | Dai, X. | Gao, J. | +13

3

Discovery of 5,6-Bis(4-methoxy-3-methylphenyl)pyridin-2-amine as a WSB1 Degrader to Inhibit Cancer Cell Metastasis

enthalten in: Journal of medicinal chemistry | 2021

von Che, J. | Jin, Z. | Yan, F. | +10

4

Discovery of 1,5-Dihydro-4H-imidazol-4-one Derivatives as Potent, Selective Antagonists of CXC Chemokine Receptor 2

enthalten in: ACS medicinal chemistry letters | 2021

von Che, J. | Wang, Z. | Shen, Z. | +6

5

Selectivity Comparison of Tumor-Imaging Probes Designed Based on Various Tumor-Targeting Strategies : A Proof of Concept Study

enthalten in: ACS applied bio materials | 2021

von Guo, R. | Wang, H. | Dong, X. | +4

6

Identification of N-phenyl-3-methoxy-4-pyridinones as orally bioavailable H3 receptor antagonists and β-amyloid aggregation inhibitors for the treatment of Alzheimer's disease

enthalten in: European journal of medicinal chemistry | 2021

von Zhang, M. | Tang, L. | Jiang, L. | +3

7

An inherently kidney-targeting near-infrared fluorophore based probe for early detection of acute kidney injury

enthalten in: Biosensors & bioelectronics | 2021

von Wang, F. | Jiang, X. | Xiang, H. | +10

8

Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells

enthalten in: European journal of medicinal chemistry | 2020

von Che, J. | Huang, F. | Zhang, M. | +12

9

Recent advances in FLT3 inhibitors for acute myeloid leukemia

enthalten in: Future medicinal chemistry | 2020

von Tong, L. | Li, X. | Hu, Y. | +1

10

Structurally novel PI3Kδ/γ dual inhibitors characterized by a seven-membered spirocyclic spacer : The SARs investigation and PK evaluation

enthalten in: European journal of medicinal chemistry | 2020

von Tao, Q. | Chen, Y. | Liang, X. | +8

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