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topic_facet:"Enzyme Inhibitors"
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PubPharm (10)
1
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
enthalten in:
European journal of medicinal chemistry
| 2020
von
Che, J.
|
Huang, F.
|
Zhang, M.
| +12
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2
Design, synthesis and biological evaluation of novel 4-alkynyl-quinoline derivatives as PI3K/mTOR dual inhibitors
enthalten in:
European journal of medicinal chemistry
| 2015
von
Lv, X.
|
Ying, H.
|
Ma, X.
| +4
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3
Metabolism of BYZX in human liver microsomes and cytosol : identification of the metabolites and metabolic pathways of BYZX
enthalten in:
PloS one
| 2013
von
Yu, L.
|
Jiang, Y.
|
Wang, L.
| +3
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4
Imidazoline derivatives : a patent review (2006--present)
enthalten in:
Expert opinion on therapeutic patents
| 2012
von
Guan, X.
|
Hu, Y.
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5
Pharmacophore identification, docking and "in silico" screening for novel CDK1 inhibitors
enthalten in:
Journal of molecular graphics & modelling
| 2012
von
Dong, X.
|
Yan, J.
|
Du, L.
| +4
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6
Discovery of novel 2-piperidinol-3-(arylsulfonyl)quinoxalines as phosphoinositide 3-kinase α (PI3Kα) inhibitors
enthalten in:
Bioorganic & medicinal chemistry
| 2012
von
Wu, P.
|
Su, Y.
|
Liu, X.
| +3
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7
Identification of novel piperazinylquinoxaline derivatives as potent phosphoinositide 3-kinase (PI3K) inhibitors
enthalten in:
PloS one
| 2012
von
Wu, P.
|
Su, Y.
|
Guan, X.
| +5
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8
Synthesis and biological evaluation of novel 2-arylamino-3-(arylsulfonyl)quinoxalines as PI3Kα inhibitors
enthalten in:
European journal of medicinal chemistry
| 2011
von
Wu, P.
|
Su, Y.
|
Liu, X.
| +10
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9
Novel 4 beta-anilino-podophyllotoxin derivatives : design synthesis and biological evaluation as potent DNA-topoisomerase II poisons and anti-MDR agents
enthalten in:
Molecular bioSystems
| 2010
von
Hu, C.
|
Xu, D.
|
Du, W.
| +6
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10
QSAR study of Akt/protein kinase B (PKB) inhibitors using support vector machine
enthalten in:
European journal of medicinal chemistry
| 2009
von
Dong, X.
|
Jiang, C.
|
Hu, H.
| +3
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1
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Thema: Enzyme Inhibitors
Medienart
10
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Zeitschriftentitel
4
European journal of medicinal chemistry
2
PloS one
1
Bioorganic & medicinal chemistry
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Expert opinion on therapeutic patents
1
Journal of molecular graphics & modelling
1
Molecular bioSystems
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Thema
Enzyme Inhibitors
10
Journal Article
5
Antineoplastic Agents
5
Research Support, Non-U.S. Gov't
4
Phosphoinositide-3 Kinase Inhibitors
3
EC 2.7.11.1
3
Quinoxalines
2
Proto-Oncogene Proteins c-akt
1
2-(4-((dimethylamino)methyl)benzylidene)-5,6-di...
1
2-(piperidin-4-ol)-3-(4-bromophenylsulfonyl)qui...
1
4-Alkynyl-quinoline
1
6PLQ3CP4P3
1
7YNJ3PO35Z
1
ABCB1 protein, human
1
ATP Binding Cassette Transporter, Subfamily B
1
ATP Binding Cassette Transporter, Subfamily B, ...
1
Alkynes
1
Aniline Compounds
1
Anti-Bacterial Agents
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Aryl Hydrocarbon Hydroxylases
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2010-2019
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