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PubPharm (49)
1
Discovery of 5,6-Bis(4-methoxy-3-methylphenyl)pyridin-2-amine as a WSB1 Degrader to Inhibit Cancer Cell Metastasis
enthalten in:
Journal of medicinal chemistry
| 2021
von
Che, J.
|
Jin, Z.
|
Yan, F.
| +10
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2
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
enthalten in:
European journal of medicinal chemistry
| 2020
von
Che, J.
|
Huang, F.
|
Zhang, M.
| +12
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3
Recent advances in FLT3 inhibitors for acute myeloid leukemia
enthalten in:
Future medicinal chemistry
| 2020
von
Tong, L.
|
Li, X.
|
Hu, Y.
| +1
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4
Structurally novel PI3Kδ/γ dual inhibitors characterized by a seven-membered spirocyclic spacer : The SARs investigation and PK evaluation
enthalten in:
European journal of medicinal chemistry
| 2020
von
Tao, Q.
|
Chen, Y.
|
Liang, X.
| +8
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5
Design, synthesis and biological evaluation of novel benzothiadiazine derivatives as potent PI3Kδ-selective inhibitors for treating B-cell-mediated malignancies
enthalten in:
European journal of medicinal chemistry
| 2019
von
Ma, X.
|
Wei, J.
|
Wang, C.
| +3
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6
Design, synthesis, and biological study of 4-[(2-nitroimidazole-1H-alkyloxyl)aniline]-quinazolines as EGFR inhibitors exerting cytotoxicities both under normoxia and hypoxia
enthalten in:
Drug design, development and therapy
| 2019
von
Cheng, W.
|
Wang, S.
|
Yang, Z.
| +2
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7
Design, synthesis and biological evaluation of pyrazol-furan carboxamide analogues as novel Akt kinase inhibitors
enthalten in:
European journal of medicinal chemistry
| 2016
von
Zhan, W.
|
Xu, L.
|
Dong, X.
| +8
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8
PARP1 : A Promising Target for the Development of PARP1-based Candidates for Anticancer Intervention
enthalten in:
Current medicinal chemistry
| 2016
von
Zhu, X.
|
Ma, X.
|
Hu, Y.
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9
Discovery of novel quinoline-based mTOR inhibitors via introducing intra-molecular hydrogen bonding scaffold (iMHBS) : The design, synthesis and biological evaluation
enthalten in:
Bioorganic & medicinal chemistry
| 2015
von
Ma, X.
|
Lv, X.
|
Qiu, N.
| +3
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10
Design, synthesis and biological evaluation of novel 4-alkynyl-quinoline derivatives as PI3K/mTOR dual inhibitors
enthalten in:
European journal of medicinal chemistry
| 2015
von
Lv, X.
|
Ying, H.
|
Ma, X.
| +4
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Thema: Antineoplastic Agents
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49
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Thema
Antineoplastic Agents
49
Journal Article
31
Research Support, Non-U.S. Gov't
13
Protein Kinase Inhibitors
9
EC 2.7.11.1
8
EC 2.3.2.27
8
Tumor Suppressor Protein p53
7
Proto-Oncogene Proteins c-mdm2
6
Review
5
Enzyme Inhibitors
5
MDM2 protein, human
5
Phosphoinositide-3 Kinase Inhibitors
5
Proto-Oncogene Proteins c-akt
5
Quinoxalines
4
1UD32YR59G
4
EC 2.4.2.30
4
EC 2.7.10.1
4
EC 3.4.22.-
4
Imidazoles
4
Proto-Oncogene Proteins c-bcl-2
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2010-2019
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