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publishDate:"[2010 TO 2019]"
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PubPharm (210)
1
2-substituted aromatic ring-pyrimidine derivative and preparation and application thereof
enthalten in:
Europäisches Patentamt
| 2019
von
LIU TAO
|
LI JIA
|
HU YONGZHOU
| +8
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2
POLYFLUORO-SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUND DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND APPLICATIONS THEREOF
enthalten in:
Europäisches Patentamt
| 2019
von
DONG XIAOWU
|
YANG BO
|
HU YONGZHOU
| +4
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3
Physicochemical-property guided design of a highly sensitive probe to image nitrosative stress in the pathology of stroke
enthalten in:
Chemical science
| 2019
von
Cheng, J.
|
Li, D.
|
Sun, M.
| +7
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4
Discovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors
enthalten in:
European journal of medicinal chemistry
| 2019
von
Zhan, W.
|
Che, J.
|
Xu, L.
| +7
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5
Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based Design
enthalten in:
Journal of medicinal chemistry
| 2019
von
Dong, X.
|
Zhan, W.
|
Zhao, M.
| +15
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6
Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino)pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies
enthalten in:
European journal of medicinal chemistry
| 2019
von
Tong, L.
|
Song, P.
|
Jiang, K.
| +10
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7
Design, synthesis and biological evaluation of novel benzothiadiazine derivatives as potent PI3Kδ-selective inhibitors for treating B-cell-mediated malignancies
enthalten in:
European journal of medicinal chemistry
| 2019
von
Ma, X.
|
Wei, J.
|
Wang, C.
| +3
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8
Phenotypic Screening-Based Identification of 3,4-Disubstituted Piperidine Derivatives as Macrophage M2 Polarization Modulators : An Opportunity for Treating Multiple Sclerosis
enthalten in:
Journal of medicinal chemistry
| 2019
von
Weng, Q.
|
Che, J.
|
Zhang, Z.
| +10
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9
Design, synthesis, and biological study of 4-[(2-nitroimidazole-1H-alkyloxyl)aniline]-quinazolines as EGFR inhibitors exerting cytotoxicities both under normoxia and hypoxia
enthalten in:
Drug design, development and therapy
| 2019
von
Cheng, W.
|
Wang, S.
|
Yang, Z.
| +2
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10
GSH Activated Biotin-tagged Near-Infrared Probe for Efficient Cancer Imaging
enthalten in:
Theranostics
| 2019
von
Guo, R.
|
Huang, F.
|
Zhang, B.
| +12
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Erscheinungsjahr: 2010-2019
Medienart
210
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European journal of medicinal chemistry
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Bioorganic & medicinal chemistry
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Molecules (Basel, Switzerland)
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Medicinal chemistry (Shariqah (United Arab Emir...
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3
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2
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2
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Thema
97
Journal Article
63
Research Support, Non-U.S. Gov't
31
Antineoplastic Agents
17
EC 2.7.11.1
17
Protein Kinase Inhibitors
10
Proto-Oncogene Proteins c-akt
10
Review
9
Apoptosis
9
EC 2.3.2.27
8
615
8
Enzyme Inhibitors
8
Proto-Oncogene Proteins c-mdm2
8
che
7
A61K: Preparations for medical, dental, or toil...
7
Caspases
7
Ketones
7
Tumor Suppressor Protein p53
6
Quinoxalines
5
A61P: Specific therapeutic activity of chemical...
5
C07D: Heterocyclic compounds (macromolecular co...
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