Suchergebnisse - "Hroch, Lukas"

PubPharm (22)

1

Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation

enthalten in: European journal of medicinal chemistry | 2023

von Benek, O. | Vaskova, M. | Miskerikova, M. | +20

2

Effects of novel 17β-hydroxysteroid dehydrogenase type 10 inhibitors on mitochondrial respiration

enthalten in: Toxicology letters | 2021

von Fišar, Z. | Musílek, K. | Benek, O. | +5

3

Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment

enthalten in: International journal of molecular sciences | 2020

von Schmidt, M. | Benek, O. | Vinklarova, L. | +13

4

Novel Benzothiazole-based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer's Disease Treatment

enthalten in: Molecules (Basel, Switzerland) | 2019

von Aitken, L. | Benek, O. | McKelvie, B. | +9

5

1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders

enthalten in: Journal of enzyme inhibition and medicinal chemistry | 2018

von Benek, O. | Hroch, L. | Aitken, L. | +8

6

Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro

enthalten in: European journal of medicinal chemistry | 2018

von Honegr, J. | Malinak, D. | Dolezal, R. | +7

7

Reduction of Folate by Dihydrofolate Reductase from Thermotoga maritima

enthalten in: Biochemistry | 2017

von Loveridge, E. | Hroch, L. | Hughes, R. | +6

8

Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment

enthalten in: Bioorganic & medicinal chemistry | 2017

von Hroch, L. | Guest, P. | Benek, O. | +10

9

6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment : Design, synthesis and in vitro evaluation

enthalten in: Medicinal chemistry (Shariqah (United Arab Emirates)) | 2017

von Benek, O. | Hroch, L. | Aitken, L. | +9

10

6-Benzothiazolyl Ureas, Thioureas and Guanidines are Potent Inhibitors of ABAD/17β-HSD10 and Potential Drugs for Alzheimer"s Disease Treatment: Design, Synthesis and in vitro Evaluation

enthalten in: Medicinal chemistry | 2017

von Benek, O. | Hroch, L. | Aitken, L. | +9