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PubPharm (110)
1
Synthesis and evaluation of indomethacin prodrugs with a diester structure that are metabolically activated by human carboxylesterases
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2024
von
Takani, D.
|
Takahashi, M.
|
Hosokawa, M.
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2
Functional roles and localization of hydrolases in the Japanese mitten crab Eriocheir japonica
enthalten in:
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
| 2024
von
Takahashi, M.
|
Takahashi, K.
|
Yamaguchi, T.
| +2
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3
Effects of steric hindrance and electron density of ester prodrugs on controlling the metabolic activation by human carboxylesterase
enthalten in:
Drug metabolism and pharmacokinetics
| 2021
von
Takahashi, M.
|
Hirota, I.
|
Nakano, T.
| +6
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4
Design, synthesis and biological evaluation of water-soluble phenytoin prodrugs considering the substrate recognition ability of human carboxylesterase 1
enthalten in:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
| 2020
von
Takahashi, M.
|
Lee, Y.
|
Kanayama, T.
| +5
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5
Structure-activity relationship of atorvastatin derivatives for metabolic activation by hydrolases
enthalten in:
Xenobiotica; the fate of foreign compounds in biological systems
| 2020
von
Mizoi, K.
|
Takahashi, M.
|
Sakai, S.
| +3
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6
Investigation of the chiral recognition ability of human carboxylesterase 1 using indomethacin esters
enthalten in:
Chirality
| 2020
von
Takahashi, M.
|
Takani, D.
|
Haba, M.
| +1
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7
Structure-activity relationship of atorvastatin derivatives for metabolic activation by hydrolases
enthalten in:
Xenobiotica
| 2020
von
Mizoi, K.
|
Takahashi, M.
|
Sakai, S.
| +3
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8
Investigation of the chiral recognition ability of human carboxylesterase 1 using indomethacin esters
enthalten in:
Chirality
| 2020
von
Takahashi, M.
|
Takani, D.
|
Haba, M.
| +1
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9
Indole-3-propionic acid has chemical chaperone activity and suppresses endoplasmic reticulum stress-induced neuronal cell death
enthalten in:
Biochemical and biophysical research communications
| 2019
von
Mimori, S.
|
Kawada, K.
|
Saito, R.
| +5
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10
Synthesis and evaluation of haloperidol ester prodrugs metabolically activated by human carboxylesterase
enthalten in:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
| 2019
von
Takahashi, M.
|
Uehara, T.
|
Nonaka, M.
| +4
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Drug metabolism and disposition
9
Drug metabolism and disposition: the biological...
8
European journal of clinical pharmacology
5
Biochemical and biophysical research communicat...
4
Archives of biochemistry and biophysics
4
Drug metabolism and pharmacokinetics
4
Pharmaceutical research
4
Xenobiotica; the fate of foreign compounds in b...
3
BMC neurology
3
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Bioorganic & medicinal chemistry letters
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Mammalian genome
3
Xenobiotica
2
Annual review of pharmacology and toxicology
2
British journal of clinical pharmacology
2
Chemico-biological interactions
2
Circulation research
2
Comparative biochemistry and physiology. Part B...
2
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Thema
51
Journal Article
31
Carboxylesterase
28
EC 3.1.1.1
24
Research Support, Non-U.S. Gov't
21
EC 3.1.1.-
20
Carboxylic Ester Hydrolases
12
Oseltamivir
12
RNA, Messenger
9
Isoenzymes
8
CES1 protein, human
8
Esters
8
Prodrugs
7
9035-51-2
7
Cytochrome P-450 Enzyme System
7
EC 1.14.14.1
6
Comparative Study
6
Prodrug
5
CYP3A protein, human
5
Cytochrome P-450 CYP3A
5
DNA, Complementary
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Erscheinungszeitraum
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1900-1999
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