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topic_facet:"Pyrimidines"
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PubPharm (9)
1
Evaluation of the drug-drug interaction potential of brigatinib using a physiologically-based pharmacokinetic modeling approach
enthalten in:
CPT: pharmacometrics & systems pharmacology
| 2024
von
Hanley, M.
|
Yeo, K.
|
Tugnait, M.
| +5
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2
Mobocertinib : Mechanism of action, clinical, and translational science
enthalten in:
Clinical and translational science
| 2024
von
Hanley, M.
|
Camidge, D.
|
Fram, R.
| +1
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3
Pharmacometric analyses and clinical evidence for brigatinib dosing in anaplastic lymphoma kinase-positive non-small cell lung cancer
enthalten in:
British journal of clinical pharmacology
| 2022
von
Gupta, N.
|
Hanley, M.
|
Sinha, V.
CommentOn: Br J Clin Pharmacol. 2022 Feb;88(4):1930-1934. - PMID 34545619
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4
Population pharmacokinetic and exposure-response analyses from ALTA-1L : Model-based analyses supporting the brigatinib dose in ALK-positive NSCLC
enthalten in:
Clinical and translational science
| 2022
von
Gupta, N.
|
Reckamp, K.
|
Camidge, D.
| +8
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5
Effect of severe renal impairment on the pharmacokinetics of brigatinib
enthalten in:
Investigational new drugs
| 2021
von
Gupta, N.
|
Hanley, M.
|
Kerstein, D.
| +4
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6
Population Pharmacokinetics of Brigatinib in Healthy Volunteers and Patients With Cancer
enthalten in:
Clinical pharmacokinetics
| 2021
von
Gupta, N.
|
Wang, X.
|
Offman, E.
| +5
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7
Brigatinib Versus Crizotinib in Advanced ALK Inhibitor-Naive ALK-Positive Non-Small Cell Lung Cancer : Second Interim Analysis of the Phase III ALTA-1L Trial
enthalten in:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
| 2020
von
Camidge, D.
|
Kim, H.
|
Ahn, M.
| +19
CommentIn: J Clin Oncol. 2020 Nov 1;38(31):3581-3583. - PMID 32897826
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8
Effects of Strong CYP2C8 or CYP3A Inhibition and CYP3A Induction on the Pharmacokinetics of Brigatinib, an Oral Anaplastic Lymphoma Kinase Inhibitor, in Healthy Volunteers
enthalten in:
Clinical pharmacology in drug development
| 2020
von
Tugnait, M.
|
Gupta, N.
|
Hanley, M.
| +5
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9
The Effect of a High-Fat Meal on the Pharmacokinetics of Brigatinib, an Oral Anaplastic Lymphoma Kinase Inhibitor, in Healthy Volunteers
enthalten in:
Clinical pharmacology in drug development
| 2019
von
Tugnait, M.
|
Gupta, N.
|
Hanley, M.
| +5
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1
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Thema: Pyrimidines
Medienart
9
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9
E-Artikel
9
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Zeitschriftentitel
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Clinical and translational science
2
Clinical pharmacology in drug development
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British journal of clinical pharmacology
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Thema
Pyrimidines
8
HYW8DB273J
8
Journal Article
8
Organophosphorus Compounds
8
Research Support, Non-U.S. Gov't
8
brigatinib
7
EC 2.7.10.1
5
Anaplastic Lymphoma Kinase
5
Protein Kinase Inhibitors
3
Clinical Trial, Phase I
3
Randomized Controlled Trial
2
304NUG5GF4
2
Comparative Study
2
Cytochrome P-450 CYP3A Inducers
2
Cytochrome P-450 CYP3A Inhibitors
2
EC 1.14.14.1
2
Itraconazole
2
Rifampin
2
VJT6J7R4TR
1
53AH36668S
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Erscheinungszeitraum
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2020-
1
2010-2019
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