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PubPharm (14)
1
Interactions between Gepotidacin and Escherichia coli Gyrase and Topoisomerase IV : Genetic and Biochemical Evidence for Well-Balanced Dual-Targeting
enthalten in:
ACS infectious diseases
| 2024
von
Oviatt, A.
|
Gibson, E.
|
Huang, J.
| +4
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2
Relationship between Gepotidacin Exposure and Prevention of On-Therapy Resistance Amplification in a Neisseria gonorrhoeae Hollow-Fiber In Vitro Infection Model
enthalten in:
Antimicrobial agents and chemotherapy
| 2020
von
VanScoy, B.
|
Scangarella-Oman, N.
|
Fikes, S.
| +6
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3
In Vitro Activity and Microbiological Efficacy of Gepotidacin from a Phase 2, Randomized, Multicenter, Dose-Ranging Study in Patients with Acute Bacterial Skin and Skin Structure Infections
enthalten in:
Antimicrobial agents and chemotherapy
| 2020
von
Scangarella-Oman, N.
|
Ingraham, K.
|
Tiffany, C.
| +9
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4
Microbiological Analysis from a Phase 2 Randomized Study in Adults Evaluating Single Oral Doses of Gepotidacin in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria gonorrhoeae
enthalten in:
Antimicrobial agents and chemotherapy
| 2018
von
Scangarella-Oman, N.
|
Hossain, M.
|
Dixon, P.
| +9
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5
Imidazopyrazinones (IPYs) : Non-Quinolone Bacterial Topoisomerase Inhibitors Showing Partial Cross-Resistance with Quinolones
enthalten in:
Journal of medicinal chemistry
| 2018
von
Jeannot, F.
|
Taillier, T.
|
Despeyroux, P.
| +15
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6
Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening
enthalten in:
Nature communications
| 2017
von
Machutta, C.
|
Kollmann, C.
|
Lind, K.
| +62
ErratumIn: Nat Commun. 2018 Jul 13;9:16227. - PMID 30004092
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7
Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase
enthalten in:
Proceedings of the National Academy of Sciences of the United States of America
| 2017
von
Chan, P.
|
Germe, T.
|
Bax, B.
| +13
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8
Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase
enthalten in:
Journal of medicinal chemistry
| 2016
von
Concha, N.
|
Huang, J.
|
Bai, X.
| +21
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9
Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin
enthalten in:
Nature communications
| 2015
von
Chan, P.
|
Srikannathasan, V.
|
Huang, J.
| +16
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10
Frequency of Spontaneous Resistance to Peptide Deformylase Inhibitor GSK1322322 in Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae
enthalten in:
Antimicrobial agents and chemotherapy
| 2015
von
Min, S.
|
Ingraham, K.
|
Huang, J.
| +10
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Thema: Anti-Bacterial Agents
Medienart
14
Aufsätze
14
E-Artikel
14
E-Ressourcen
Zeitschriftentitel
5
Antimicrobial agents and chemotherapy
2
Bioorganic & medicinal chemistry letters
2
Journal of medicinal chemistry
2
Nature communications
1
ACS infectious diseases
1
Nature
1
Proceedings of the National Academy of Sciences...
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Thema
Anti-Bacterial Agents
14
Journal Article
7
Research Support, Non-U.S. Gov't
6
EC 5.99.1.3
4
Acenaphthenes
4
DNA Gyrase
4
DVF0PR037D
4
Heterocyclic Compounds, 3-Ring
4
Topoisomerase II Inhibitors
4
gepotidacin
3
5E8K9I0O4U
3
Ciprofloxacin
2
Amidohydrolases
2
DNA Topoisomerase IV
2
DNA Topoisomerases, Type II
2
EC 3.5.-
2
EC 3.5.1.88
2
EC 5.99.1.-
2
Neisseria gonorrhoeae
2
Research Support, U.S. Gov't, Non-P.H.S.
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Erscheinungszeitraum
3
2020-
11
2010-2019
Erscheinungsjahr(e)
Von:
Bis:
Sprache
14
Englisch
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