Suchergebnisse - "Gaymes, Terry J"

PubPharm (20)

1

Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells : potential for therapy of myeloid leukemia and myelodysplastic syndromes

enthalten in: Haematologica | 2021

von Gaymes, T. | Shall, S. | Macpherson, L. | +4

ErratumFor: Haematologica. 2009 May;94(5):638-46. - PMID 19407318

2

FLT3 and JAK2 Mutations in Acute Myeloid Leukemia Promote Interchromosomal Homologous Recombination and the Potential for Copy Neutral Loss of Heterozygosity

enthalten in: Cancer research | 2017

von Gaymes, T. | Mohamedali, A. | Eiliazadeh, A. | +2

3

FLT3 and JAK2 mutations in acute myeloid leukemia promote inter-chromosomal homologous recombination and the potential for copy neutral loss of heterozygosity (CN-LOH)

enthalten in: Cancer research | 2017

von Gaymes, T. | Mohamedali, A. | Eiliazadeh, A. | +2

4

Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies

enthalten in: Haematologica | 2013

von Gaymes, T. | Mohamedali, A. | Patterson, M. | +8

5

Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells : potential for therapy of myeloid leukemia and myelodysplastic syndromes

enthalten in: Haematologica | 2009

von Gaymes, T. | Shall, S. | MacPherson, L. | +4

ErratumIn: Haematologica. 2021 Aug 01;106(8):2294. - PMID 34333961

6

Myelodysplastic Syndromes - Inhibitors of poly-ADP-ribose polymerase (PARD) induce apoptosis of myeloid leukemic cells: Potential for therapy of myeloid leukemia and myelodysplastic syndromes - Hematopoietic cells from patients with acute myeloid leukemia and myelodysplastic syndrome often have defects in DNA repair processes. This study shows that these defects make the cells susceptible to induction of apoptosis by poly ADP-ribose polymerase (PARD) inhibitors.

enthalten in: Haematologica, the hematology journal | 2009

von Gaymes, T. | Shall, S. | MacPherson, L. | +4

7

Chromosomal instability syndromes are sensitive to poly ADP-ribose polymerase inhibitors

enthalten in: Haematologica | 2008

von Gaymes, T. | Shall, S. | Farzaneh, F. | +1

8

BCL6-mediated attenuation of DNA damage sensing triggers growth arrest and senescence through a p53-dependent pathway in a cell context-dependent manner

enthalten in: The Journal of biological chemistry | 2008

von Ranuncolo, S. | Wang, L. | Polo, J. | +6

9

BCL6-mediated Attenuation of DNA Damage Sensing Triggers Growth Arrest and Senescence through a p53-dependent Pathway in a Cell Context-dependent Manner

enthalten in: The journal of biological chemistry | 2008

von Ranuncolo, S. | Wang, L. | Polo, J. | +6

10

Brief Reports - Bone Marrow Failure - Chromosomal instability syndromes are sensitive to poly ADP ribose polymerase inhibitors - The findings of this study suggest that chromosomal instability disorders that have DNA repair defects and increased propensity to transform to leukemia are potential targets for poly ADP ribose polymerase inhibitors.

enthalten in: Haematologica, the hematology journal | 2008

von Gaymes, T. | Shall, S. | Farzaneh, F. | +1