Suchergebnisse - "Gaymes, Terry"

PubPharm (24)

1

A Phase I trial of talazoparib in patients with advanced hematologic malignancies

enthalten in: International journal of hematologic oncology | 2021

von Gopal, A. | Popat, R. | Mattison, R. | +8

2

Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells : potential for therapy of myeloid leukemia and myelodysplastic syndromes

enthalten in: Haematologica | 2021

von Gaymes, T. | Shall, S. | Macpherson, L. | +4

ErratumFor: Haematologica. 2009 May;94(5):638-46. - PMID 19407318

3

Introducing Novel Molecular-based Method for Quantification of Homologous Recombination Efficiency

enthalten in: bioRxiv.org | 2021

von Dibbasey, M. | Gaymes, T.

4

FLT3 and JAK2 Mutations in Acute Myeloid Leukemia Promote Interchromosomal Homologous Recombination and the Potential for Copy Neutral Loss of Heterozygosity

enthalten in: Cancer research | 2017

von Gaymes, T. | Mohamedali, A. | Eiliazadeh, A. | +2

5

The Use of PARP Inhibitors in Cancer Therapy : Use as Adjuvant with Chemotherapy or Radiotherapy, Use as a Single Agent in Susceptible Patients, and Techniques Used to Identify Susceptible Patients

enthalten in: Methods in molecular biology (Clifton, N.J.) | 2017

von Shall, S. | Gaymes, T. | Farzaneh, F. | +2

6

FLT3 and JAK2 mutations in acute myeloid leukemia promote inter-chromosomal homologous recombination and the potential for copy neutral loss of heterozygosity (CN-LOH)

enthalten in: Cancer research | 2017

von Gaymes, T. | Mohamedali, A. | Eiliazadeh, A. | +2

7

Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies

enthalten in: Haematologica | 2013

von Gaymes, T. | Mohamedali, A. | Patterson, M. | +8

8

The use of PARP inhibitors in cancer therapy : use as adjuvant with chemotherapy or radiotherapy; use as a single agent in susceptible patients; techniques used to identify susceptible patients

enthalten in: Methods in molecular biology (Clifton, N.J.) | 2011

von Shall, S. | Gaymes, T. | Farzaneh, F. | +2

9

Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells : potential for therapy of myeloid leukemia and myelodysplastic syndromes

enthalten in: Haematologica | 2009

von Gaymes, T. | Shall, S. | MacPherson, L. | +4

ErratumIn: Haematologica. 2021 Aug 01;106(8):2294. - PMID 34333961

10

Myelodysplastic Syndromes - Inhibitors of poly-ADP-ribose polymerase (PARD) induce apoptosis of myeloid leukemic cells: Potential for therapy of myeloid leukemia and myelodysplastic syndromes - Hematopoietic cells from patients with acute myeloid leukemia and myelodysplastic syndrome often have defects in DNA repair processes. This study shows that these defects make the cells susceptible to induction of apoptosis by poly ADP-ribose polymerase (PARD) inhibitors.

enthalten in: Haematologica, the hematology journal | 2009

von Gaymes, T. | Shall, S. | MacPherson, L. | +4