Suchergebnisse - "Fullerton, Aaron"

PubPharm (21)

1

Discovery of TRPA1 Antagonist GDC-6599 : Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease

enthalten in: Journal of medicinal chemistry | 2024

von Terrett, J. | Ly, J. | Katavolos, P. | +53

2

Towards in vitro models for reducing or replacing the use of animals in drug testing

enthalten in: Nature biomedical engineering | 2023

von Stresser, D. | Kopec, A. | Hewitt, P. | +24

3

A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma

enthalten in: Leukemia | 2022

von Kakiuchi-Kiyota, S. | Ross, T. | Wallweber, H. | +27

4

Perspectives on the evaluation and adoption of complex in vitro models in drug development : Workshop with the FDA and the pharmaceutical industry (IQ MPS Affiliate)

enthalten in: ALTEX | 2022

von Baran, S. | Brown, P. | Baudy, A. | +24

5

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2 : Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy

enthalten in: Journal of medicinal chemistry | 2021

von Dragovich, P. | Pillow, T. | Blake, R. | +34

6

In vitro assessment of farnesoid X receptor antagonism to predict drug-induced liver injury risk

enthalten in: Archives of toxicology | 2020

von Norona, L. | Fullerton, A. | Lawson, C. | +6

7

An in vitro quantitative systems pharmacology approach for deconvolving mechanisms of drug-induced, multilineage cytopenias

enthalten in: PLoS computational biology | 2020

von Wilson, J. | Lu, D. | Corr, N. | +2

8

Application of microphysiological systems in biopharmaceutical research and development

enthalten in: Lab on a chip | 2020

von Peterson, N. | Mahalingaiah, P. | Fullerton, A. | +1

9

General Principles for the Validation of Proarrhythmia Risk Prediction Models : An Extension of the CiPA In Silico Strategy

enthalten in: Clinical pharmacology and therapeutics | 2020

von Li, Z. | Mirams, G. | Yoshinaga, T. | +39

10

Sequential azacitidine and lenalidomide for patients with relapsed and refractory acute myeloid leukemia : Clinical results and predictive modeling using computational analysis

enthalten in: Leukemia research | 2019

von Stevens, B. | Winters, A. | Gutman, J. | +15