Suchergebnisse - "Feng, Da"

PubPharm (11)

1

In situ click chemistry-based discovery of 1,2,3-triazole-derived diarylpyrimidines as novel HIV-1 NNRTIs by exploiting the tolerant region I in binding pocket

enthalten in: Bioorganic & medicinal chemistry | 2023

von Sun, Y. | Feng, D. | Zhou, Z. | +6

2

Identification of "dual-site"-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase

enthalten in: European journal of medicinal chemistry | 2023

von Feng, D. | Zuo, X. | Zhao, F. | +8

3

Disubstituted pyrimidine-5-carboxamide derivatives as novel HIV-1 NNRTIs : Crystallographic overlay-based molecular design, synthesis, and biological evaluation

enthalten in: European journal of medicinal chemistry | 2023

von Feng, D. | Lin, H. | Jiang, L. | +10

4

Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

enthalten in: Molecules (Basel, Switzerland) | 2022

von Feng, D. | Lin, H. | Jiang, L. | +8

5

Design, synthesis, and antiviral evaluation of novel piperidine-substituted arylpyrimidines as HIV-1 NNRTIs by exploring the hydrophobic channel of NNIBP

enthalten in: Bioorganic chemistry | 2021

von Zhang, T. | Zhou, Z. | Zalloum, W. | +11

6

Targeting dual tolerant regions of binding pocket : Discovery of novel morpholine-substituted diarylpyrimidines as potent HIV-1 NNRTIs with significantly improved water solubility

enthalten in: European journal of medicinal chemistry | 2020

von Wang, Z. | Kang, D. | Feng, D. | +7

7

Structure-Activity Relationship Exploration of NNIBP Tolerant Region I Leads to Potent HIV-1 NNRTIs

enthalten in: ACS infectious diseases | 2020

von Kang, D. | Sun, Y. | Murugan, N. | +8

8

Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-d]pyrimidine derivatives as potent HIV-1 NNRTIs

enthalten in: Acta pharmaceutica Sinica. B | 2020

von Kang, D. | Feng, D. | Ginex, T. | +10

9

In situ click chemistry-based rapid discovery of novel HIV-1 NNRTIs by exploiting the hydrophobic channel and tolerant regions of NNIBP

enthalten in: European journal of medicinal chemistry | 2020

von Kang, D. | Feng, D. | Jing, L. | +8

10

Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors by exploring the structure-activity relationship of solvent-exposed regions I

enthalten in: Chemical biology & drug design | 2019

von Kang, D. | Wang, Z. | Chen, M. | +11