Suchergebnisse - "Feng, Da"

PubPharm (14)

1

In situ click chemistry-based discovery of 1,2,3-triazole-derived diarylpyrimidines as novel HIV-1 NNRTIs by exploiting the tolerant region I in binding pocket

enthalten in: Bioorganic & medicinal chemistry | 2023

von Sun, Y. | Feng, D. | Zhou, Z. | +6

2

Identification of "dual-site"-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase

enthalten in: European journal of medicinal chemistry | 2023

von Feng, D. | Zuo, X. | Zhao, F. | +8

3

Disubstituted pyrimidine-5-carboxamide derivatives as novel HIV-1 NNRTIs : Crystallographic overlay-based molecular design, synthesis, and biological evaluation

enthalten in: European journal of medicinal chemistry | 2023

von Feng, D. | Lin, H. | Jiang, L. | +10

4

Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

enthalten in: Molecules (Basel, Switzerland) | 2022

von Feng, D. | Lin, H. | Jiang, L. | +8

5

Structure-Based Discovery and Characterization of a Preclinical Drug Candidate for the Treatment of HIV-1 Infection

enthalten in: Viruses | 2022

von Kang, D. | Yang, J. | Kong, L. | +10

6

Discovery, optimization, and target identification of novel coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitors

enthalten in: European journal of medicinal chemistry | 2021

von Kang, D. | Urhan, �. | Wei, F. | +10

7

Design, synthesis, and antiviral evaluation of novel piperidine-substituted arylpyrimidines as HIV-1 NNRTIs by exploring the hydrophobic channel of NNIBP

enthalten in: Bioorganic chemistry | 2021

von Zhang, T. | Zhou, Z. | Zalloum, W. | +11

8

Design, synthesis, and evaluation of "dual-site"-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase

enthalten in: European journal of medicinal chemistry | 2021

von Feng, D. | Zuo, X. | Jing, L. | +10

9

Targeting dual tolerant regions of binding pocket : Discovery of novel morpholine-substituted diarylpyrimidines as potent HIV-1 NNRTIs with significantly improved water solubility

enthalten in: European journal of medicinal chemistry | 2020

von Wang, Z. | Kang, D. | Feng, D. | +7

10

Structure-Activity Relationship Exploration of NNIBP Tolerant Region I Leads to Potent HIV-1 NNRTIs

enthalten in: ACS infectious diseases | 2020

von Kang, D. | Sun, Y. | Murugan, N. | +8