SEMA4D blocking antibody, pepinemab, is a novel potential treatment for neurodegenerative disease : Clinical proof of concept in Phase 2 HD study supports ongoing clinical development in Phase 1/2 AD study

enthalten in: Alzheimer's & Dementia | 2023

von Fisher, T. | Evans, E. | Boise, M. | +12

Evidence that semaphorin 4D is upregulated in neurons in Huntington’s and Alzheimer’s diseases : Effects of a SEMA4D blocking antibody on FDG‐PET in a clinical trial, and treatment rationale for its use in AD

enthalten in: Alzheimer's & Dementia | 2020

von Evans, E. | Fisher, T. | Leonard, J. | +9

P3‐007 : VX15 ANTI‐SEMAPHORIN 4D ANTIBODY (PEPINEMAB) INCREASES FDG‐PET SIGNAL AND IS A POTENTIAL TREATMENT FOR ALZHEIMER'S DISEASE

enthalten in: Alzheimer's & Dementia | 2019

von Fisher, T. | Evans, E. | Leonard, J. | +7