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PubPharm (11)
1
Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations
enthalten in:
Cancer discovery
| 2024
von
Varkaris, A.
|
Fece de la Cruz, F.
|
Martin, E.
| +28
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2
Sotorasib is a pan-RASG12C inhibitor capable of driving clinical response in NRASG12C cancers
enthalten in:
Cancer discovery
| 2024
von
Rubinson, D.
|
Tanaka, N.
|
Fece de la Cruz, F.
| +10
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3
Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2024
von
Wu, Q.
|
Ellis, H.
|
Siravegna, G.
| +9
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4
Vertical Pathway Inhibition Overcomes Adaptive Feedback Resistance to KRASG12C Inhibition
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2020
von
Ryan, M.
|
Fece de la Cruz, F.
|
Phat, S.
| +5
CommentIn: Clin Cancer Res. 2020 Apr 1;26(7):1538-1540. - PMID 32001483
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5
Co-occurring Alterations in the RAS-MAPK Pathway Limit Response to MET Inhibitor Treatment in MET Exon 14 Skipping Mutation-Positive Lung Cancer
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2020
von
Rotow, J.
|
Gui, P.
|
Wu, W.
| +22
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6
TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion-Positive Intrahepatic Cholangiocarcinoma
enthalten in:
Cancer discovery
| 2019
von
Goyal, L.
|
Shi, L.
|
Liu, L.
| +39
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7
Epigenetic and transcriptional dysregulation of VWA2 associated with a MYC-driven oncogenic program in colorectal cancer
enthalten in:
Scientific reports
| 2018
von
González, B.
|
Fece de la Cruz, F.
|
Samuelsson, J.
| +2
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8
MEK inhibitors block growth of lung tumours with mutations in ataxia-telangiectasia mutated
enthalten in:
Nature communications
| 2016
von
Smida, M.
|
Fece de la Cruz, F.
|
Kerzendorfer, C.
| +13
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9
Synthetic lethal vulnerabilities of cancer
enthalten in:
Annual review of pharmacology and toxicology
| 2015
von
Fece de la Cruz, F.
|
Gapp, B.
|
Nijman, S.
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10
Synthetic lethal vulnerabilities of cancer
enthalten in:
Annual review of pharmacology and toxicology
| 2015
von
Fece de la Cruz, F.
|
Gapp, B.
|
Nijman, S.
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8
Research Support, Non-U.S. Gov't
5
Protein Kinase Inhibitors
4
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3
Biomarkers, Tumor
3
EC 2.7.10.1
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FGFR2 protein, human
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Pyrimidines
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1
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53AH36668S
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2010-2019
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