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PubPharm (212)
1
Discovery and Mechanistic Studies of Dual-Target Hits for Carbonic Anhydrase IX and VEGFR-2 as Potential Agents for Solid Tumors : X-ray, In Vitro, In Vivo, and In Silico Investigations of Coumarin-Based Thiazoles
enthalten in:
Journal of medicinal chemistry
| 2024
von
Hefny, S.
|
El-Moselhy, T.
|
El-Din, N.
| +11
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2
Multi-target rational design and synthesis of novel diphenyl-tethered pyrazolopyrimidines targeting EGFR and topoisomerase II with potential DNA intercalation and apoptosis induction
enthalten in:
Bioorganic chemistry
| 2024
von
Gaber, A.
|
Abo Elmaaty, A.
|
Sharaky, M.
| +5
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3
Phthalimide-tethered isatins as novel poly(ADP-ribose) polymerase inhibitors : Design, synthesis, biological evaluations, and molecular modeling investigations
enthalten in:
Archiv der Pharmazie
| 2024
von
El Hassab, M.
|
El-Hafeez, A.
|
Almahli, H.
| +4
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4
Design and synthesis of benzo[b]thiophene-based hybrids as novel antitubercular agents against MDR/XDR Mycobacterium tuberculosis
enthalten in:
Archiv der Pharmazie
| 2024
von
Al-Warhi, T.
|
Rashad, N.
|
Almahli, H.
| +4
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5
Identification of new anti-mycobacterial agents based on quinoline-isatin hybrids targeting enoyl acyl carrier protein reductase (InhA)
enthalten in:
Bioorganic chemistry
| 2024
von
Khaleel, E.
|
Sabt, A.
|
Korycka-Machala, M.
| +9
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6
New pyrazolylindolin-2-one based coumarin derivatives as anti-melanoma agents : design, synthesis, dual BRAFV600E/VEGFR-2 inhibition, and computational studies
enthalten in:
RSC advances
| 2024
von
Sabt, A.
|
Khedr, M.
|
Eldehna, W.
| +4
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7
An overview of recent advancements in small molecules suppression of oncogenic signaling of K-RAS : an updated review
enthalten in:
Molecular diversity
| 2024
von
Sabt, A.
|
Tawfik, H.
|
Khaleel, E.
| +4
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8
A multidisciplinary approach to the antioxidant and hepatoprotective activities of Arbutus pavarii Pampan fruit; in vitro and in Vivo biological evaluations, and in silico investigations
enthalten in:
Journal of enzyme inhibition and medicinal chemistry
| 2024
von
Elshibani, F.
|
Alamami, A.
|
Mohammed, H.
| +9
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9
Discovery of Novel Pyridazine-Tethered Sulfonamides as Carbonic Anhydrase II Inhibitors for the Management of Glaucoma
enthalten in:
Journal of medicinal chemistry
| 2024
von
Tawfik, H.
|
Saleh, M.
|
Ammara, A.
| +11
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10
In vitro biological evaluation and in silico insights into the antiviral activity of standardized olive leaves extract against SARS-CoV-2
enthalten in:
PloS one
| 2024
von
Majrashi, T.
|
El Hassab, M.
|
Mahmoud, S.
| +6
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212
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201
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Zeitschriftentitel
51
Journal of enzyme inhibition and medicinal chem...
48
European journal of medicinal chemistry
18
Molecules (Basel, Switzerland)
17
Bioorganic chemistry
9
Archiv der Pharmazie
6
International journal of molecular sciences
5
Journal of medicinal chemistry
5
PloS one
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ACS omega
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Frontiers in pharmacology
2
Future medicinal chemistry
2
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Molecular diversity
Alle anzeigen ...
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Thema
192
Journal Article
89
Antineoplastic Agents
47
Carbonic Anhydrase Inhibitors
45
EC 4.2.1.1
42
Sulfonamides
37
EC 2.7.10.1
35
Carbonic Anhydrases
32
Protein Kinase Inhibitors
27
Carbonic Anhydrase IX
27
Research Support, Non-U.S. Gov't
26
Isatin
26
Vascular Endothelial Growth Factor Receptor-2
22
82X95S7M06
19
Synthesis
19
apoptosis
18
Anticancer
17
Antigens, Neoplasm
16
molecular docking
16
synthesis
13
Carbonic anhydrase inhibitors
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Erscheinungszeitraum
151
2020-
61
2010-2019
Erscheinungsjahr(e)
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Sprache
206
Englisch
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