Suchergebnisse - "Edink, Ewald"

PubPharm (21)

1

To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?

enthalten in: International journal of molecular sciences | 2023

von Zheng, Y. | Schroeder, S. | Kanev, G. | +18

2

From recipe to research : introducing undergraduate students to the nature of science using a hybrid practical course centred on drug discovery for neglected diseases

enthalten in: Drug discovery today | 2021

von Wijtmans, M. | Edink, E. | van Linden, O. | +4

3

Discovery of Diaryl Ether Substituted Tetrahydrophthalazinones as TbrPDEB1 Inhibitors Following Structure-Based Virtual Screening

enthalten in: Frontiers in chemistry | 2020

von de Heuvel, E. | Kooistra, A. | Edink, E. | +11

4

Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors

enthalten in: Bioorganic & medicinal chemistry | 2019

von de Heuvel, E. | Singh, A. | Edink, E. | +16

5

Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity

enthalten in: Journal of medicinal chemistry | 2018

von Blaazer, A. | Singh, A. | de Heuvel, E. | +24

6

Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals

enthalten in: Bioorganic & medicinal chemistry | 2016

von Veerman, J. | van den Bergh, T. | Orrling, K. | +11

7

4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction : Structure-Activity Relationships Exploration with the Aid of Molecular Modeling

enthalten in: Journal of medicinal chemistry | 2016

von Trist, I. | Nannetti, G. | Tintori, C. | +12

8

4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling

enthalten in: Journal of medicinal chemistry | 2016

von Trist, I. | Nannetti, G. | Tintori, C. | +12

9

Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals

enthalten in: Bioorganic & medicinal chemistry | 2016

von Veerman, J. | van den Bergh, T. | Orrling, K. | +11

10

Fragment-based screening in tandem with phenotypic screening provides novel antiparasitic hits

enthalten in: Journal of biomolecular screening | 2015

von Blaazer, A. | Orrling, K. | Shanmugham, A. | +9