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topic_facet:"ErbB Receptors"
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PubPharm (31)
1
Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations
enthalten in:
Journal of medicinal chemistry
| 2022
von
Chen, H.
|
Lai, M.
|
Zhang, T.
| +9
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2
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
enthalten in:
Cancer science
| 2022
von
Liu, Y.
|
Lai, M.
|
Li, S.
| +20
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3
The HDAC inhibitor GCJ-490A suppresses c-Met expression through IKKα and overcomes gefitinib resistance in non-small cell lung cancer
enthalten in:
Cancer biology & medicine
| 2022
von
He, T.
|
Gao, Y.
|
Fang, Y.
| +5
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4
BRD4 inhibition boosts the therapeutic effects of epidermal growth factor receptor-targeted chimeric antigen receptor T cells in glioblastoma
enthalten in:
Molecular therapy : the journal of the American Society of Gene Therapy
| 2021
von
Xia, L.
|
Liu, J.
|
Zheng, Z.
| +6
CommentIn: Mol Ther. 2021 Oct 6;29(10):2896-2897. - PMID 34559988
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5
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
enthalten in:
Molecular cancer
| 2020
von
Zhang, T.
|
Qu, R.
|
Chan, S.
| +18
ErratumIn: Mol Cancer. 2021 Aug 17;20(1):102. - PMID 34404402
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6
Application of Paclitaxel-loaded EGFR Peptide-conjugated Magnetic Polymeric Liposomes for Liver Cancer Therapy
enthalten in:
Current medical science
| 2020
von
Lin, Z.
|
Ding, J.
|
Sun, G.
| +5
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7
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition
enthalten in:
Acta pharmacologica Sinica
| 2019
von
Zhang, K.
|
Shen, Q.
|
Fang, Y.
| +3
ErratumIn: Acta Pharmacol Sin. 2020 May;41(5):733-734. - PMID 32060412
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8
Bispecific Antibodies Enable Synthetic Agonistic Receptor-Transduced T Cells for Tumor Immunotherapy
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2019
von
Karches, C.
|
Benmebarek, M.
|
Schmidbauer, M.
| +18
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9
Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFRL858R/T790M/C797S)
enthalten in:
Journal of medicinal chemistry
| 2019
von
Shen, J.
|
Zhang, T.
|
Zhu, S.
| +11
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10
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5- d]pyrimidine-2,4(1 H,3 H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation
enthalten in:
Journal of medicinal chemistry
| 2018
von
Hao, Y.
|
Lyu, J.
|
Qu, R.
| +11
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Thema: ErbB Receptors
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31
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29
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6
Acta pharmacologica Sinica
5
Bioorganic & medicinal chemistry
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Thema
31
EC 2.7.10.1
ErbB Receptors
31
Journal Article
22
Research Support, Non-U.S. Gov't
16
Antineoplastic Agents
15
EGFR protein, human
15
Protein Kinase Inhibitors
7
Pyrimidines
7
Quinazolines
4
Gefitinib
4
Receptor, ErbB-2
4
S65743JHBS
3
Angiogenesis Inhibitors
3
Aniline Compounds
3
NSCLC
2
AZD9291
2
Acrylamides
2
EGFR T790M/L858R
2
Irreversible EGFR inhibitor
2
Mutant selective inhibitors
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2020-
21
2010-2019
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2000-2009
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