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journalStr:"Journal of medicinal chemistry"
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PubPharm (48)
1
Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion
enthalten in:
Journal of medicinal chemistry
| 2023
von
Fu, Y.
|
Huang, Y.
|
Zhou, C.
| +5
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2
Discovery and Structure-Based Design of Inhibitors of the WD Repeat-Containing Protein 5 (WDR5)-MYC Interaction
enthalten in:
Journal of medicinal chemistry
| 2023
von
Ding, J.
|
Liu, L.
|
Chiang, Y.
| +17
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3
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer
enthalten in:
Journal of medicinal chemistry
| 2022
von
Zhang, S.
|
Chen, X.
|
Wu, C.
| +11
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4
Structure-Aided Design, Synthesis, and Biological Evaluation of Potent and Selective Non-Nucleoside Inhibitors Targeting Protein Arginine Methyltransferase 5
enthalten in:
Journal of medicinal chemistry
| 2022
von
Rong, D.
|
Zhou, K.
|
Fang, W.
| +10
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5
Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations
enthalten in:
Journal of medicinal chemistry
| 2022
von
Chen, H.
|
Lai, M.
|
Zhang, T.
| +9
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6
Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases
enthalten in:
Journal of medicinal chemistry
| 2020
von
Mainolfi, N.
|
Ehara, T.
|
Karki, R.
| +46
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7
Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors
enthalten in:
Journal of medicinal chemistry
| 2020
von
Zhang, S.
|
Gong, C.
|
Su, M.
| +9
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8
Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFRL858R/T790M/C797S)
enthalten in:
Journal of medicinal chemistry
| 2019
von
Shen, J.
|
Zhang, T.
|
Zhu, S.
| +11
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9
Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia
enthalten in:
Journal of medicinal chemistry
| 2019
von
Guo, Z.
|
Zhang, Z.
|
Yang, H.
| +15
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10
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5- d]pyrimidine-2,4(1 H,3 H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation
enthalten in:
Journal of medicinal chemistry
| 2018
von
Hao, Y.
|
Lyu, J.
|
Qu, R.
| +11
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Zeitschrift: Journal of medicinal chemistry
Medienart
48
Aufsätze
28
E-Artikel
28
E-Ressourcen
20
Gedruckte Aufsätze
Zeitschriftentitel
Journal of medicinal chemistry
Thema
30
Journal Article
26
Research Support, Non-U.S. Gov't
11
EC 2.7.10.1
10
Protein Kinase Inhibitors
7
Antineoplastic Agents
5
ErbB Receptors
4
Enzyme Inhibitors
3
EGFR protein, human
3
Pyrimidines
3
Thiazoles
2
67256-21-7
2
8L70Q75FXE
2
AE28F7PNPL
2
Adenosine Triphosphate
2
Anti-Bacterial Agents
2
Cell Proliferation - drug effects
2
Diterpenes
2
EC 2.1.1.319
2
EC 2.7.10.2
2
EC 3.6.1.-
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Erscheinungszeitraum
46
2000-
2
1900-1999
Erscheinungsjahr(e)
Von:
Bis:
Sprache
36
Englisch
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