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journalStr:"European journal of medicinal chemistry"
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PubPharm (27)
1
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
enthalten in:
European journal of medicinal chemistry
| 2023
von
Wang, P.
|
Zhu, W.
|
Wang, Y.
| +12
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2
Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzofuran IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma
enthalten in:
European journal of medicinal chemistry
| 2023
von
Chen, Y.
|
Ning, Y.
|
Chen, Z.
| +7
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3
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer
enthalten in:
European journal of medicinal chemistry
| 2021
von
Gao, F.
|
Chen, X.
|
Lu, J.
| +9
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4
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRASG12C inhibitors
enthalten in:
European journal of medicinal chemistry
| 2021
von
Xiao, X.
|
Lai, M.
|
Song, Z.
| +4
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5
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors
enthalten in:
European journal of medicinal chemistry
| 2021
von
Xiang, H.
|
Wang, X.
|
Chen, Y.
| +12
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6
Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma
enthalten in:
European journal of medicinal chemistry
| 2020
von
Chen, Y.
|
Bai, G.
|
Ning, Y.
| +8
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7
Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation
enthalten in:
European journal of medicinal chemistry
| 2018
von
Yan, Q.
|
Chen, Y.
|
Tang, B.
| +10
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8
Design, synthesis and biological evaluation of tetrahydronaphthyridine derivatives as bioavailable CDK4/6 inhibitors for cancer therapy
enthalten in:
European journal of medicinal chemistry
| 2018
von
Zha, C.
|
Deng, W.
|
Fu, Y.
| +11
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9
Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors
enthalten in:
European journal of medicinal chemistry
| 2018
von
Chen, X.
|
Huan, X.
|
Liu, Q.
| +8
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10
Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC
enthalten in:
European journal of medicinal chemistry
| 2017
von
Chen, L.
|
Fu, W.
|
Feng, C.
| +12
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Zeitschrift: European journal of medicinal chemistry
Medienart
27
Aufsätze
18
E-Artikel
18
E-Ressourcen
9
Gedruckte Aufsätze
Zeitschriftentitel
European journal of medicinal chemistry
Thema
18
Journal Article
12
Antineoplastic Agents
10
Protein Kinase Inhibitors
6
EC 2.7.10.1
6
Research Support, Non-U.S. Gov't
5
EC 2.7.11.1
5
Pyrimidines
4
Receptor Protein-Tyrosine Kinases
3
EC 2.4.2.30
3
Piperazines
3
Poly(ADP-ribose) Polymerase Inhibitors
3
Proto-Oncogene Proteins c-akt
2
ALK protein, human
2
Anaplastic Lymphoma Kinase
2
Angiogenesis Inhibitors
2
Anti-cancer
2
Carbazoles
2
ErbB Receptors
2
IRAK4 protein, human
2
Interleukin-1 Receptor-Associated Kinases
Alle anzeigen ...
weniger ...
Erscheinungszeitraum
6
2020-
17
2010-2019
4
2000-2009
Erscheinungsjahr(e)
Von:
Bis:
Sprache
20
Englisch
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