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journalStr:"WHO International Clinical Trials Registry Platform"
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PubPharm (7.078)
1
A Phase 4 clinical trial to measure the effect of Obeticholic acid against a placebo, in conjunction with standard treatment, on selected clinical measurements in patients with the liver disease, Primary Biliary Cholangitis.The COBALT Study Clinical Outcomes with OBeticholic Acid in Liver Treatment (COBALT). : A Phase 4, Double Blind, Randomized, Placebo Controlled, Multicenter Study Evaluating the Effect of Obeticholic Acid on Clinical Outcomes in Subjects with Primary Biliary Cholangitis. The COBALT Study Clinical Outcomes with OBeticholic Acid in Liver Treatment (COBALT).
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| 2023
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2
A Phase 2, Multicenter, Open-Label Extension (OLE) Study to Observe the Long-Term Efficacy, Safety, and Tolerability of Repeated Administration of ABT 494 in Subjects with Crohn's Disease : A Phase 2, Multicenter, Open-Label Extension (OLE) Study to Observe the Long-Term Efficacy, Safety, and Tolerability of Repeated Administration of ABT-494 in Subjects with Crohn's Disease
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| 2023
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3
Comparison of Two Different Golimumab Dosing Regimens for Ulcerative Colitis : Exposure-response of golimumab during maintenance in ulcerative colitis: An exploratory Pharmacokinetics/Pharmacodynamics comparison of different dose regimens
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| 2023
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4
A study evaluating the efficacy and safety of Etrasimod in the treatment of patients with moderately to severely active Ulcerative Colitis : A Phase 3, Randomized, Double Blind, Placebo Controlled, 12 Week Study to Assess the Efficacy and Safety of Etrasimod in Subjects with Moderately to Severely Active Ulcerative Colitis - ELEVATE UC 12
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| 2023
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5
A Blinded Study to Evaluate the Efficacy and Safety of Two Adalimumab Doses in Subjects with Moderately to Severely Active Crohn's Disease and Evidence of Mucosal Ulceration : A Multicenter, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Two Adalimumab Induction Regimens in Subjects with Moderately to Severely Active Crohn's Disease and Evidence of Mucosal Ulceration
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| 2023
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6
A Clinical trial to evaluate safety, and effectiveness of Selonsertib in Subjects with Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis. : A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis.
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| 2023
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7
Clinical Study to Evaluation the Efficacy and Safety of PRV-6527 an Inhibitor of Colony Stimulating Factor-1 Receptor, in patients with Moderately to Severely Active Crohn’s Disease : A Phase 2a, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Study to Evaluate the Efficacy and Safety of Oral PRV-6527 (JNJ-40346527), an Inhibitor of Colony Stimulating Factor-1 Receptor, in Subjects with Moderately to Severely Active Crohn’s Disease - PRovention INvestigation in Crohn’s DiseasE (PRINCE)
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| 2023
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8
Research study to determine whether an investigational drug, SHP647, is safe and effective in the treatment of moderate to severe Ulcerative Colitis, compared with placebo (dummy treatment) – using a randomised and blinded study design (investigator and patients are not aware whether they receive study drug or placebo)(FIGARO UC 303). : A Phase 3 Randomized, Double-blind, Placebo controlled, Parallel group Efficacy and Safety Study of SHP647 as Maintenance Therapy in Subjects With Moderate to Severe Ulcerative Colitis (FIGARO UC 303) - FIGARO UC 303
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| 2023
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9
A trial of a new drug, obeticholic acid, in patients with diarrhoea caused by bile acids : OBADIAH-2: A randomised, double-blind, placebo-controlled trial of two doses of obeticholic acid and placebo in patients with primary bile acid diarrhoea - OBADIAH-2 version 0.9
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| 2023
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10
Tirzepatide versus placebo in NASH : A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study Comparingthe Efficacy and Safety of Tirzepatide versus Placebo in Patients withNonalcoholic Steatohepatitis (NASH) - SYNERGY-NASH
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| 2023
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Zeitschrift: WHO International Clinical Trials Registry Platform
Medienart
7.078
Aufsätze
7.078
E-Artikel
7.078
E-Ressourcen
Zeitschriftentitel
WHO International Clinical Trials Registry Plat...
Thema
7.078
610
7.058
Study Type: Interventional
4.286
Recruitment Status: Not yet recruiting
3.056
Phase: Phase 3
2.512
Recruitment Status: Authorised-recruitment may ...
2.174
Phase: Phase 2
484
Phase: Phase 4
204
Medical Condition: Ulcerative Colitis MedDRA ve...
176
Medical Condition: Ulcerative colitis MedDRA ve...
168
Medical Condition: Ulcerative Colitis MedDRA ve...
136
Medical Condition: Moderately to Severely Activ...
116
Medical Condition: Crohn's Disease (CD) MedDRA ...
116
Medical Condition: Ulcerative Colitis MedDRA ve...
88
Medical Condition: Crohn's Disease MedDRA versi...
88
Medical Condition: Moderately to Severely Activ...
84
Medical Condition: Crohn's disease MedDRA versi...
76
Recruitment Status: Completed
64
Medical Condition: Diabetic Gastroparesis MedDR...
62
Medical Condition: Ulcerative Colitis (UC) MedD...
62
Phase: Phase 1
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Erscheinungszeitraum
3.942
2020-
3.136
2010-2019
Erscheinungsjahr(e)
Von:
Bis:
Sprache
7.008
Englisch
52
Unbestimmt
6
Spanisch
4
Frisian
4
Latein
2
Niederländisch
2
Isländisch
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