Suchergebnisse - "Cytochrome P-450 CYP3A Inhibitors"

PubPharm (1.720)

71

Itacitinib Population Pharmacokinetics and Exposure-Response in Patients With Acute Graft-Versus-Host Disease

enthalten in: Journal of clinical pharmacology | 2023

von Chen, X. | Xun, Z. | Yuska, B. | +2

72

Enhancement of the Oral Availability of Cabazitaxel Using the Cytochrome P450 3A (CYP3A) Inhibitor Ritonavir in Mice

enthalten in: Molecular pharmaceutics | 2023

von Loos, N. | Martins, M. | de Jong, D. | +4

73

Physiologically based pharmacokinetic modeling (PBPK) to predict drug-drug interactions for encorafenib. Part II. Prospective predictions in hepatic and renal impaired populations with clinical inhibitors and inducers

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2023

von Kollipara, S. | Ahmed, T. | Praveen, S.

74

Identification of CYP3A4 inhibitors as potential anti-cancer agents using pharmacoinformatics approach

enthalten in: Journal of molecular modeling | 2023

von Wanjari, P. | Rath, A. | Sathe, R. | +1

75

Evaluation of the Potential for Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions for Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor (FXR) Agonist

enthalten in: Clinical pharmacokinetics | 2023

von Younis, I. | Weber, E. | Nelson, C. | +5

76

Tiered approach to evaluate the CYP3A victim and perpetrator drug-drug interaction potential for vonoprazan using PBPK modeling and clinical data to inform labeling

enthalten in: CPT: pharmacometrics & systems pharmacology | 2023

von Mulford, D. | Ramsden, D. | Zhang, L. | +5

77

High hepatic and plasma exposures of atorvastatin in subjects harboring impaired cytochrome P450 3A4∗16 modeled after virtual administrations and possibly associated with statin intolerance found in the Japanese adverse drug event report database

enthalten in: Drug metabolism and pharmacokinetics | 2023

von Adachi, K. | Ohyama, K. | Tanaka, Y. | +5

78

Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro

enthalten in: Drug metabolism and disposition: the biological fate of chemicals | 2023

von Paludetto, M. | Kurkela, M. | Kahma, H. | +3

79

Effect of CYP3A inducer/inhibitor and licorice on hepatotoxicity and in vivo metabolism of main alkaloids of Euodiae Fructus based on UPLC-Q-Exactive-MS

enthalten in: Journal of ethnopharmacology | 2023

von Ren, K. | Wang, R. | Fang, S. | +5

80

Evaluating the impact of co-administered drug and disease on ripretinib exposure : A physiologically-based pharmacokinetic modeling approach

enthalten in: Chemico-biological interactions | 2023

von Pan, C. | Cheng, Y. | He, Q. | +5