Suchergebnisse - "Cyclooxygenase 2 Inhibitors"

PubPharm (1.971)

1

Design, synthesis and molecular docking of novel D-ring substituted steroidal 4,5-dihydropyrazole thiazole derivatives that act as iNOS/COX-2 inhibitors with potent anti-inflammatory activity against LPS-induced RAW264.7 macrophage cells

enthalten in: The Journal of steroid biochemistry and molecular biology | 2024

von Fang, S. | Huang, X. | Cai, F. | +3

2

Enhancing therapeutic efficacy in triple-negative breast cancer and melanoma : synergistic effects of modulated electro-hyperthermia (mEHT) with NSAIDs especially COX-2 inhibition in in vivo models

enthalten in: Molecular oncology | 2024

von Giunashvili, N. | Thomas, J. | Schvarcz, C. | +9

3

Repurposed Drugs Celecoxib and Fmoc-L-Leucine Alone and in Combination as Temozolomide-Resistant Antiglioma Agents-Comparative Studies on Normal and Immortalized Cell Lines, and on C. elegans

enthalten in: International journal of molecular sciences | 2024

von Uram, �. | Pieńkowska, N. | Misiorek, M. | +4

4

Synthesis, molecular docking, analgesic, anti-inflammatory, and ulcerogenic evaluation of thiophene-pyrazole candidates as COX, 5-LOX, and TNF-α inhibitors

enthalten in: Inflammopharmacology | 2024

von Khadri, M. | Ramu, R. | Simha, N. | +1

5

Towards safer anti-inflammatory therapy : synthesis of new thymol-pyrazole hybrids as dual COX-2/5-LOX inhibitors

enthalten in: Journal of enzyme inhibition and medicinal chemistry | 2023

von El-Miligy, M. | Al-Kubeisi, A. | Bekhit, M. | +3

6

Fragment merging approach for the design of thiazole/thiazolidine clubbed pyrazoline derivatives as anti-inflammatory agents : Synthesis, biopharmacological evaluation and molecular modeling studies

enthalten in: Bioorganic chemistry | 2023

von Elgohary, M. | Abd El Hadi, S. | Abo-Ashour, M. | +4

7

Effects of the anti-inflammatory drug celecoxib on cell death signaling in human colon cancer

enthalten in: Naunyn-Schmiedeberg's archives of pharmacology | 2023

von Maruyama, R. | Kiyohara, Y. | Kudo, Y. | +1

8

Development of novel pyrazole, imidazo[1,2-b]pyrazole, and pyrazolo[1,5-a]pyrimidine derivatives as a new class of COX-2 inhibitors with immunomodulatory potential

enthalten in: European journal of medicinal chemistry | 2023

von Ayman, R. | Abusaif, M. | Radwan, A. | +2

9

Novel pyrazole-based COX-2 inhibitors as potential anticancer agents : Design, synthesis, cytotoxic effect against resistant cancer cells, cell cycle arrest, apoptosis induction and dual EGFR/Topo-1 inhibition

enthalten in: Bioorganic chemistry | 2023

von Halim, P. | Sharkawi, S. | Labib, M.

10

Discovery of novel pyrazole and pyrazolo[1,5-a]pyrimidine derivatives as cyclooxygenase inhibitors (COX-1 and COX-2) using molecular modeling simulation

enthalten in: Archiv der Pharmazie | 2023

von Ayman, R. | Radwan, A. | Elmetwally, A. | +2

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