Suchergebnisse - "Curtin, Nicola"

PubPharm (15)

1

Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System

enthalten in: Molecular cancer therapeutics | 2015

von Parrish, K. | Cen, L. | Murray, J. | +11

2

A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation

enthalten in: Cancer chemotherapy and pharmacology | 2013

von Plummer, R. | Lorigan, P. | Steven, N. | +10

3

Vasoactivity of AG014699, a clinically active small molecule inhibitor of poly(ADP-ribose) polymerase : a contributory factor to chemopotentiation in vivo?

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2009

von Ali, M. | Telfer, B. | McCrudden, C. | +9

4

Inhibition of poly(ADP-ribose) polymerase-1 enhances temozolomide and topotecan activity against childhood neuroblastoma

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2009

von Daniel, R. | Rozanska, A. | Thomas, H. | +9

5

Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines

enthalten in: Molecular cancer therapeutics | 2009

von Clarke, M. | Mulligan, E. | Grogan, P. | +9

6

Phase I study of the poly(ADP-ribose) polymerase inhibitor, AG014699, in combination with temozolomide in patients with advanced solid tumors

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2008

von Plummer, R. | Jones, C. | Middleton, M. | +14

7

Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial

enthalten in: Molecular cancer therapeutics | 2007

von Thomas, H. | Calabrese, C. | Batey, M. | +9

8

Temozolomide pharmacodynamics in patients with metastatic melanoma : dna damage and activity of repair enzymes O6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2005

von Plummer, E. | Middleton, M. | Jones, C. | +12

9

PARP inhibitors for cancer therapy

enthalten in: Expert reviews in molecular medicine | 2005

von Curtin, N.

10

Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors

enthalten in: Bioorganic & medicinal chemistry letters | 2004

von White, A. | Curtin, N. | Eastman, B. | +9