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topic_facet:"Morpholines"
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PubPharm (11)
1
DNA-PK inhibition by NU7441 sensitizes breast cancer cells to ionizing radiation and doxorubicin
enthalten in:
Breast cancer research and treatment
| 2014
von
Ciszewski, W.
|
Tavecchio, M.
|
Dastych, J.
| +1
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2
1-substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones endowed with dual DNA-PK/PI3-K inhibitory activity
enthalten in:
Journal of medicinal chemistry
| 2013
von
Cano, C.
|
Saravanan, K.
|
Bailey, C.
| +14
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3
Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination
enthalten in:
Cancer chemotherapy and pharmacology
| 2012
von
Tavecchio, M.
|
Munck, J.
|
Cano, C.
| +2
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4
Targeting the DNA double strand break repair machinery in prostate cancer
enthalten in:
PloS one
| 2011
von
Shaheen, F.
|
Znojek, P.
|
Fisher, A.
| +7
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5
Poly(ADP-Ribose) polymerase-1 and DNA-dependent protein kinase have equivalent roles in double strand break repair following ionizing radiation
enthalten in:
International journal of radiation oncology, biology, physics
| 2009
von
Mitchell, J.
|
Smith, G.
|
Curtin, N.
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6
Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase
enthalten in:
Journal of medicinal chemistry
| 2007
von
Hollick, J.
|
Rigoreau, L.
|
Cano-Soumillac, C.
| +16
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7
Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441
enthalten in:
Cancer research
| 2006
von
Zhao, Y.
|
Thomas, H.
|
Batey, M.
| +7
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8
Discovery of potent chromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK) using a small-molecule library approach
enthalten in:
Journal of medicinal chemistry
| 2005
von
Hardcastle, I.
|
Cockcroft, X.
|
Curtin, N.
| +8
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9
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
enthalten in:
Cancer research
| 2004
von
Hickson, I.
|
Zhao, Y.
|
Richardson, C.
| +7
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10
Effects of novel inhibitors of poly(ADP-ribose) polymerase-1 and the DNA-dependent protein kinase on enzyme activities and DNA repair
enthalten in:
Oncogene
| 2004
von
Veuger, S.
|
Curtin, N.
|
Smith, G.
| +1
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Thema: Morpholines
Medienart
11
Aufsätze
6
Gedruckte Aufsätze
5
E-Artikel
5
E-Ressourcen
Zeitschriftentitel
3
Cancer research
3
Journal of medicinal chemistry
1
Breast cancer research and treatment
1
Cancer chemotherapy and pharmacology
1
International journal of radiation oncology, bi...
1
Oncogene
1
PloS one
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weniger ...
Thema
11
EC 2.7.11.1
11
Journal Article
Morpholines
10
DNA-Activated Protein Kinase
9
Chromones
9
Research Support, Non-U.S. Gov't
6
8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen...
5
DNA-Binding Proteins
5
Protein Serine-Threonine Kinases
4
Ataxia Telangiectasia Mutated Proteins
4
Protein Kinase Inhibitors
4
Radiation-Sensitizing Agents
3
6PLQ3CP4P3
3
ATM protein, human
3
Cell Cycle Proteins
3
Etoposide
3
Nuclear Proteins
3
Poly(ADP-ribose) Polymerase Inhibitors
3
Pyrones
3
Tumor Suppressor Proteins
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Erscheinungszeitraum
4
2010-2019
7
2000-2009
Erscheinungsjahr(e)
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Sprache
11
Englisch
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