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PubPharm (22)
1
PARP inhibitor rucaparib induces changes in NAD levels in cells and liver tissues as assessed by MRS
enthalten in:
NMR in biomedicine
| 2017
von
Almeida, G.
|
Bawn, C.
|
Galler, M.
| +6
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2
Ovarian Cancers Harbor Defects in Nonhomologous End Joining Resulting in Resistance to Rucaparib
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2017
von
McCormick, A.
|
Donoghue, P.
|
Dixon, M.
| +6
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3
Strategies Employed for the Development of PARP Inhibitors
enthalten in:
Methods in molecular biology (Clifton, N.J.)
| 2017
von
Canan, S.
|
Maegley, K.
|
Curtin, N.
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4
Advanced Ovarian Cancer Displays Functional Intratumor Heterogeneity That Correlates to Ex Vivo Drug Sensitivity
enthalten in:
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
| 2016
von
O'Donnell, R.
|
Kaufmann, A.
|
Woodhouse, L.
| +4
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5
Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer
enthalten in:
British journal of cancer
| 2016
von
Drew, Y.
|
Ledermann, J.
|
Hall, G.
| +14
CommentIn: Br J Cancer. 2016 Mar 29;114(7):713-5. - PMID 27022824
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6
Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio-resistance in breast cancer
enthalten in:
Molecular oncology
| 2016
von
Alsubhi, N.
|
Middleton, F.
|
Abdel-Fatah, T.
| +12
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7
Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System
enthalten in:
Molecular cancer therapeutics
| 2015
von
Parrish, K.
|
Cen, L.
|
Murray, J.
| +11
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8
PARP activity in peripheral blood lymphocytes as a predictive biomarker for PARP inhibition in tumor tissues - A population pharmacokinetic/pharmacodynamic analysis of rucaparib
enthalten in:
Clinical pharmacology in drug development
| 2015
von
Wang, D.
|
Li, C.
|
Sun, W.
| +7
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9
Vasoactivity of rucaparib, a PARP-1 inhibitor, is a complex process that involves myosin light chain kinase, P2 receptors, and PARP itself
enthalten in:
PloS one
| 2015
von
McCrudden, C.
|
O'Rourke, M.
|
Cherry, K.
| +14
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10
The use of ovarian cancer cells from patients undergoing surgery to generate primary cultures capable of undergoing functional analysis
enthalten in:
PloS one
| 2014
von
O Donnell, R.
|
McCormick, A.
|
Mukhopadhyay, A.
| +9
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Thema: Indoles
Medienart
22
Aufsätze
18
E-Artikel
18
E-Ressourcen
4
Gedruckte Aufsätze
Zeitschriftentitel
6
Clinical cancer research : an official journal ...
2
Journal of medicinal chemistry
2
Molecular cancer therapeutics
2
PloS one
1
Bioorganic & medicinal chemistry letters
1
British journal of cancer
1
Cancer chemotherapy and pharmacology
1
Clinical pharmacology in drug development
1
International journal of gynecological cancer :...
1
Journal of the National Cancer Institute
1
Methods in molecular biology (Clifton, N.J.)
1
Molecular oncology
1
NMR in biomedicine
1
Nature medicine
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Thema
Indoles
22
Journal Article
17
8237F3U7EH
17
rucaparib
15
Poly(ADP-ribose) Polymerase Inhibitors
14
Research Support, Non-U.S. Gov't
8
EC 2.4.2.30
7
7GR28W0FJI
7
Antineoplastic Agents
7
Dacarbazine
7
Temozolomide
7
YF1K15M17Y
6
Enzyme Inhibitors
6
Poly(ADP-ribose) Polymerases
3
7M7YKX2N15
3
BRCA1 Protein
3
Poly (ADP-Ribose) Polymerase-1
3
Topotecan
2
0U46U6E8UK
2
BRCA2 Protein
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Erscheinungszeitraum
15
2010-2019
7
2000-2009
Erscheinungsjahr(e)
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Sprache
22
Englisch
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