Suchergebnisse - "Chou, Kang-Jye"

PubPharm (21)

1

Discovery of TRPA1 Antagonist GDC-6599 : Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease

enthalten in: Journal of medicinal chemistry | 2024

von Terrett, J. | Ly, J. | Katavolos, P. | +53

2

Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists : Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy

enthalten in: Journal of medicinal chemistry | 2021

von Terrett, J. | Chen, H. | Shore, D. | +36

3

Preclinical assessment of the ADME, efficacy and drug-drug interaction potential of a novel NAMPT inhibitor

enthalten in: Xenobiotica; the fate of foreign compounds in biological systems | 2019

von Liederer, B. | Cheong, J. | Chou, K. | +9

4

Preclinical assessment of the ADME, efficacy and drug-drug interaction potential of a novel NAMPT inhibitor

enthalten in: Xenobiotica | 2019

von Liederer, B. | Cheong, J. | Chou, K. | +9

5

Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development

enthalten in: Journal of medicinal chemistry | 2016

von Blake, J. | Burkard, M. | Chan, J. | +28

6

Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development

enthalten in: Journal of medicinal chemistry | 2016

von Blake, J. | Burkard, M. | Chan, J. | +28

7

INJECTABLE SUSTAINED RELEASE DELIVERY DEVICES

enthalten in: Europäisches Patentamt | 2015

von CHOU KANG-JYE | GUO HONG | ASHTON PAUL | +2

8

In vitro and in vivo evaluation of amorphous solid dispersions generated by different bench-scale processes, using griseofulvin as a model compound

enthalten in: The AAPS journal | 2013

von Chiang, P. | Cui, Y. | Ran, Y. | +10

9

In Vitro and In Vivo Evaluation of Amorphous Solid Dispersions Generated by Different Bench-Scale Processes, Using Griseofulvin as a Model Compound

enthalten in: The AAPS journal | 2013

von Chiang, P. | Cui, Y. | Ran, Y. | +10

10

In Vitro and In Vivo Evaluation of Amorphous Solid Dispersions Generated by Different Bench-Scale Processes, Using Griseofulvin as a Model Compound

enthalten in: AAPS PharmSci | 2013

von Chiang, P. | Cui, Y. | Ran, Y. | +10