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PubPharm (29)
1
Fenebrutinib in H1 antihistamine-refractory chronic spontaneous urticaria : a randomized phase 2 trial
enthalten in:
Nature medicine
| 2021
von
Metz, M.
|
Sussman, G.
|
Gagnon, R.
| +13
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2
Efficacy, Safety, and Pharmacodynamic Effects of the Bruton's Tyrosine Kinase Inhibitor Fenebrutinib (GDC-0853) in Systemic Lupus Erythematosus : Results of a Phase II, Randomized, Double-Blind, Placebo-Controlled Trial
enthalten in:
Arthritis & rheumatology (Hoboken, N.J.)
| 2021
von
Isenberg, D.
|
Furie, R.
|
Jones, N.
| +20
CommentIn: Arthritis Rheumatol. 2021 Oct;73(10):1773-1775. - PMID 34042321
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3
Efficacy, Safety, and Pharmacodynamic Effects of the Bruton’s Tyrosine Kinase Inhibitor Fenebrutinib (GDC‐0853) in Systemic Lupus Erythematosus : Results of a Phase II, Randomized, Double‐Blind, Placebo‐Controlled Trial
enthalten in:
Arthritis & Rheumatology
| 2021
von
Isenberg, D.
|
Furie, R.
|
Jones, N.
| +20
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4
Understanding the Effect of Hydroxypropyl-β-Cyclodextrin on Fenebrutinib Absorption in an Itraconazole-Fenebrutinib Drug-Drug Interaction Study
enthalten in:
Clinical pharmacology and therapeutics
| 2020
von
Durk, M.
|
Jones, N.
|
Liu, J.
| +8
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5
Antibody-mediated activation of the FGFR1/Klothoβ complex corrects metabolic dysfunction and alters food preference in obese humans
enthalten in:
Proceedings of the National Academy of Sciences of the United States of America
| 2020
von
Baruch, A.
|
Wong, C.
|
Chinn, L.
| +12
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6
Physiologically-Based Pharmacokinetic Model-Informed Drug Development for Fenebrutinib : Understanding Complex Drug-Drug Interactions
enthalten in:
CPT: pharmacometrics & systems pharmacology
| 2020
von
Chen, Y.
|
Ma, F.
|
Jones, N.
| +6
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7
Fenebrutinib versus Placebo or Adalimumab in Rheumatoid Arthritis : A Randomized, Double-Blind, Phase II Trial (ANDES Study)
enthalten in:
Arthritis & rheumatology (Hoboken, N.J.)
| 2020
von
Cohen, S.
|
Tuckwell, K.
|
Katsumoto, T.
| +15
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8
Complex DDI by Fenebrutinib and the Use of Transporter Endogenous Biomarkers to Elucidate the Mechanism of DDI
enthalten in:
Clinical pharmacology and therapeutics
| 2020
von
Jones, N.
|
Yoshida, K.
|
Salphati, L.
| +3
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9
Fenebrutinib Versus Placebo or Adalimumab in Rheumatoid Arthritis : A Randomized, Double‐Blind, Phase II Trial
enthalten in:
Arthritis & Rheumatology
| 2020
von
Cohen, S.
|
Tuckwell, K.
|
Katsumoto, T.
| +15
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10
Complex DDI by Fenebrutinib and the Use of Transporter Endogenous Biomarkers to Elucidate the Mechanism of DDI
enthalten in:
Clinical Pharmacology & Therapeutics
| 2020
von
Jones, N.
|
Yoshida, K.
|
Salphati, L.
| +3
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1
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19
Journal Article
12
Research Support, Non-U.S. Gov't
10
Research Support, N.I.H., Extramural
8
fenebrutinib
7
E9L2885WUL
7
Piperazines
7
Pyridones
5
ABCB1 protein, human
5
ATP Binding Cassette Transporter, Subfamily B
5
ATP Binding Cassette Transporter, Subfamily B, ...
5
Randomized Controlled Trial
4
Protein Kinase Inhibitors
3
ATP-Binding Cassette Transporters
3
Agammaglobulinaemia Tyrosine Kinase
3
Clinical Trial, Phase I
3
EC 1.14.14.1
3
EC 2.7.10.2
2
99DK7FVK1H
2
ABCC4 protein, human
2
ABCG2 protein, human
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2010-2019
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2000-2009
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