Suchergebnisse - "Charnley, Adam K"

PubPharm (22)

1

Correction to Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel

enthalten in: ACS medicinal chemistry letters | 2020

von Haile, P. | Casillas, L. | Bury, M. | +32

ErratumFor: ACS Med Chem Lett. 2018 Sep 26;9(10):1039-1044. - PMID 30344914

2

Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors

enthalten in: ACS medicinal chemistry letters | 2019

von Haffner, C. | Charnley, A. | Aquino, C. | +23

3

Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases

enthalten in: Journal of medicinal chemistry | 2019

von Haile, P. | Casillas, L. | Votta, B. | +30

4

Author Correction : Design of amidobenzimidazole STING receptor agonists with systemic activity

enthalten in: Nature | 2019

von Ramanjulu, J. | Pesiridis, G. | Yang, J. | +42

ErratumFor: Nature. 2018 Dec;564(7736):439-443. - PMID 30405246

5

Design of amidobenzimidazole STING receptor agonists with systemic activity

enthalten in: Nature | 2018

von Ramanjulu, J. | Pesiridis, G. | Yang, J. | +42

CommentIn: Nat Rev Drug Discov. 2018 Dec 28;18(1):15. - PMID 30591729

6

Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel

enthalten in: ACS medicinal chemistry letters | 2018

von Haile, P. | Casillas, L. | Bury, M. | +31

ErratumIn: ACS Med Chem Lett. 2020 Jun 02;11(6):1353. - PMID 32551024

7

The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase

enthalten in: Journal of medicinal chemistry | 2016

von Haile, P. | Votta, B. | Marquis, R. | +32

8

The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase

enthalten in: Journal of medicinal chemistry | 2016

von Haile, P. | Votta, B. | Marquis, R. | +32

9

Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors : Foundations for understanding inhibitor selectivity

enthalten in: Bioorganic & medicinal chemistry | 2015

von Charnley, A. | Convery, M. | Lakdawala Shah, A. | +15

10

Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors: Foundations for understanding inhibitor selectivity

enthalten in: Bioorganic & medicinal chemistry | 2015

von Charnley, A. | Convery, M. | Lakdawala Shah, A. | +15