Suchergebnisse - "Chan, Alex H. Y."

PubPharm (15)

1

Evaluation of Ketoclomazone and its Analogues as Inhibitors of Thiamine Diphosphate (ThDP)-dependent Enzymes

enthalten in: chemRxiv.org | 2024

von Chan, A. | Ho, T. | Fathoni, I. | +4

2

Thiamine analogues featuring amino-oxetanes as potent and selective inhibitors of pyruvate dehydrogenase

enthalten in: Bioorganic & medicinal chemistry letters | 2024

von Chan, A. | Ho, T. | Leeper, F.

3

Design of thiamine analogues for inhibition of thiamine diphosphate (ThDP)-dependent enzymes : Systematic investigation through Scaffold-Hopping and C2-Functionalisation

enthalten in: Bioorganic chemistry | 2023

von Chan, A. | Ho, T. | Irfan, R. | +6

4

Open-chain thiamine analogues as potent inhibitors of thiamine pyrophosphate (TPP)-dependent enzymes

enthalten in: Organic & biomolecular chemistry | 2023

von Chan, A. | Ho, T. | Leeper, F.

5

Inhibition of Thiamine Diphosphate-Dependent Enzymes by Triazole-Based Thiamine Analogues

enthalten in: ACS medicinal chemistry letters | 2023

von Chan, A. | Ho, T. | Fathoni, I. | +3

6

Furan-based inhibitors of pyruvate dehydrogenase : SAR study, biochemical evaluation and computational analysis

enthalten in: Organic & biomolecular chemistry | 2023

von Chan, A. | Ho, T. | Parle, D. | +1

7

Strategies on Designing Thiamine Analogues for Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes: Systematic Investigation through Scaffold Switching and C2-Functionalisation

enthalten in: chemRxiv.org | 2023

von Chan, A. | Ho, T. | Irfan, R. | +6

8

Strategies on Designing Thiamine Analogues for Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes: Systematic Investigation through Scaffold Switching and C2-Functionalisation

enthalten in: chemRxiv.org | 2023

von Chan, A. | Ho, T. | Irfan, R. | +6

9

Correction : Thiamine analogues as inhibitors of pyruvate dehydrogenase and discovery of a thiamine analogue with non-thiamine related antiplasmodial activity

enthalten in: RSC medicinal chemistry | 2023

von Chan, A. | Fathoni, I. | Ho, T. | +2

ErratumFor: RSC Med Chem. 2022 Jun 7;13(7):817-821. - PMID 35919337

10

Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes by Triazole-based Thiamine Analogues

enthalten in: chemRxiv.org | 2023

von Chan, A. | Ho, T. | Fathoni, I. | +3